ArticleJournal of applied physiology (Bethesda, Md. : 1985)2011
Responses of neurons in the rostral ventrolateral medulla to whole body rotations: comparisons in decerebrate and conscious cats.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 38 citations in OpenAlex.
- Rhythmic firing of neurons in the medulla of conscious freely behaving rats: rhythmic coupling with baroreceptor input.Pflugers Archiv : European journal of physiology · 2023Article
- Integration of vestibular and hindlimb inputs by vestibular nucleus neurons: multisensory influences on postural control.Journal of neurophysiology · 2021Article
- Responses of neurons in the rostral ventrolateral medulla of conscious cats to anticipated and passive movements.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
- Responses of Neurons in the Medullary Lateral Tegmental Field and Nucleus Tractus Solitarius to Vestibular Stimuli in Conscious Felines.Frontiers in neurology · 2020Article
- Development of manganese-enhanced magnetic resonance imaging of the rostral ventrolateral medulla of conscious rats: Importance of normalization and comparison with other regions of interest.NMR in biomedicine · 2018Article
- Neurons in the pontomedullary reticular formation receive converging inputs from the hindlimb and labyrinth.Experimental brain research · 2017Article
- Deciphering the Neural Control of Sympathetic Nerve Activity: Status Report and Directions for Future Research.Frontiers in neuroscience · 2017Review
- Vestibular Modulation of Sympathetic Nerve Activity to Muscle and Skin in Humans.Frontiers in neurology · 2017Review
- Descending Influences on Vestibulospinal and Vestibulosympathetic Reflexes.Frontiers in neurology · 2017Review
- Vestibular Activation Habituates the Vasovagal Response in the Rat.Frontiers in neurology · 2017Article
- The response of the vestibulosympathetic reflex to linear acceleration in the rat.Journal of neurophysiology · 2016Article
- Vestibular nucleus neurons respond to hindlimb movement in the conscious cat.Journal of neurophysiology · 2016Article
- A Model of Blood Pressure, Heart Rate, and Vaso-Vagal Responses Produced by Vestibulo-Sympathetic Activation.Frontiers in neuroscience · 2016Article
- Hindlimb movement modulates the activity of rostral fastigial nucleus neurons that process vestibular input.Experimental brain research · 2015Article
- Integration of vestibular and gastrointestinal inputs by cerebellar fastigial nucleus neurons: multisensory influences on motion sickness.Experimental brain research · 2014Article
- Integration of vestibular and emetic gastrointestinal signals that produce nausea and vomiting: potential contributions to motion sickness.Experimental brain research · 2014Review
- Neck proprioceptors contribute to the modulation of muscle sympathetic nerve activity to the lower limbs of humans.Experimental brain research · 2014Article
- Vestibulo-sympathetic responses.Comprehensive Physiology · 2014Review
- Vasovagal oscillations and vasovagal responses produced by the vestibulo-sympathetic reflex in the rat.Frontiers in neurology · 2014Article
- Additive role of the vestibular end organ and baroreceptors on the regulation of blood pressure in rats.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2013Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
The responses to vestibular stimulation of brain stem neurons that regulate sympathetic outflow and blood flow have been studied extensively in decerebrate preparations, but not in conscious animals. In the present study, we compared the responses of neurons in the rostral ventrolateral medulla (RVLM), a principal region of the brain stem involved in the regulation of blood pressure, to whole body rotations of conscious and decerebrate cats. In both preparations, RVLM neurons exhibited similar levels of spontaneous activity (median of ∼17 spikes/s). The firing of about half of the RVLM neurons recorded in decerebrate cats was modulated by rotations; these cells were activated by vertical tilts in a variety of directions, with response characteristics suggesting that their labyrinthine inputs originated in otolith organs. The activity of over one-third of RVLM neurons in decerebrate animals was altered by stimulation of baroreceptors; RVLM units with and without baroreceptor signals had similar responses to rotations. In contrast, only 6% of RVLM neurons studied in conscious cats exhibited cardiac-related activity, and the firing of just 1% of the cells was modulated by rotations. These data suggest that the brain stem circuitry mediating vestibulosympathetic reflexes is highly sensitive to changes in body position in space but that the responses to vestibular stimuli of neurons in the pathway are suppressed by higher brain centers in conscious animals. The findings also raise the possibility that autonomic responses to a variety of inputs, including those from the inner ear, could be gated according to behavioral context and attenuated when they are not necessary.
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