ReviewCurrent opinion in chemical biology2011
Computational protein design: engineering molecular diversity, nonnatural enzymes, nonbiological cofactor complexes, and membrane proteins.
Review in Current opinion in chemical biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering.International journal of molecular sciences · 2020Review
- Application of conventional molecular dynamics simulation in evaluating the stability of apomyoglobin in urea solution.Scientific reports · 2017Article
- Biomolecular engineering for nanobio/bionanotechnology.Nano convergence · 2017Review
- Computational strategies for the design of new enzymatic functions.Archives of biochemistry and biophysics · 2015Review
- Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Chemical Society reviews · 2015Review
- Protein design: toward functional metalloenzymes.Chemical reviews · 2014Review
- A protein engineered to bind uranyl selectively and with femtomolar affinity.Nature chemistry · 2014Article
- Optimizing scoring function of protein-nucleic acid interactions with both affinity and specificity.PloS one · 2013Article
- Effective inter-residue contact definitions for accurate protein fold recognition.BMC bioinformatics · 2012Article
- Computational design of a Diels-Alderase from a thermophilic esterase: the importance of dynamics.Journal of computer-aided molecular design · 2012Article
- A glimpse of enzymology within the idea of systems.Science China. Life sciences · 2012Article
- Computational design of membrane proteins.Structure (London, England : 1993) · 2012Review
- Computational Enzyme Design: Advances, hurdles and possible ways forward.Computational and structural biotechnology journal · 2012Review
- Computational approaches for rational design of proteins with novel functionalities.Computational and structural biotechnology journal · 2012Review
- RETRACTED: Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine.PLoS computational biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Computational and theoretical methods are advancing protein design as a means to create and investigate proteins. Such efforts further our capacity to control, design and understand biomolecular structure, sequence and function. Herein, the focus is on some recent applications that involve using theoretical and computational methods to guide the design of protein sequence ensembles, new enzymes, proteins with novel cofactors, and membrane proteins.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.