Evidence map›Paper›PMID 21492496›Full record

ReviewEpidemiology and infection2011

Meningococcal disease in Asia: an under-recognized public health burden.

A Vyse, J M Wolter, J Chen, T Ng, M Soriano-Gabarro

Registry-linked trialAbstract readReview
In one paragraph

Review in Epidemiology and infection, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03263403 (A Randomized Observer-blinded Controlled Non-inferiority Trial to Evaluate the Immunogenicity of Locally Manufactured Meningococcal ACWY Vaccine 'Ingovax ACWY' in Bangladeshi Healthy Adults.), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03263403 phase2 / phase3completednot on this mapstarted 2017, after this paper: background citation

A Randomized Observer-blinded Controlled Non-inferiority Trial to Evaluate the Immunogenicity of Locally Manufactured Meningococcal ACWY Vaccine 'Ingovax ACWY' in Bangladeshi Healthy Adults.

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2017 to 2018Enrolled88ConditionsMeningococcal VaccineArmsIngovax ACWY, Quadri Meningo
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. The spread of chloramphenicol-resistant Neisseria meningitidis in Southeast Asia.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  15. Review
  16. Observational
  17. Article
  18. Meningococcal Vaccinations.Infectious diseases and therapy · 2016
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A VyseGlaxoSmithKline Biologicals Group of Companies, Wavre, Belgium.
J M WolterIndependent Consultant, Brisbane, Australia.
J ChenGlaxoSmithKline Biologicals Group of Companies, Wavre, Belgium.
T NgGlaxoSmithKline Biologicals Group of Companies, Wavre, Belgium.
M Soriano-GabarroGlaxoSmithKline Biologicals Group of Companies, Wavre, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A literature search traced existing information on meningococcal disease in Asia. Reviewed data describing the epidemiology of meningococcal disease in Asia are incomplete, due in part to absence of surveillance in many countries, poor bacterial detection methods and social and healthcare barriers to disease reporting. This suggests that meningococcal disease in some Asian countries may be under-recognized, with a need to introduce/improve existing surveillance and case identification systems. Nevertheless, in some developing Asian countries, the disease burden may be significant. Serogroup A meningococcal epidemics are responsible for high morbidity and mortality in some countries and continue to be an ongoing threat, particularly in developing countries. There is an increasing role played by serogroups C, Y, and W-135 in invasive disease, indicating evolving meningococcal disease epidemiology in some countries. Multivalent meningococcal conjugate vaccines offer new opportunities in the region for reducing the meningococcal disease burden.

Indexed as

AsiaCost of IllnessHumansMeningococcal InfectionsPopulation Surveillance

Identifiers

PMID21492496
PMCPMC3105449

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.