SynthesisBMC gastroenterology2011
Polyethylene glycol vs. sodium phosphate for bowel preparation: a treatment arm meta-analysis of randomized controlled trials.
Synthesis in BMC gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05836064 (GastroBot), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
GastroBot: a New Artificial Intelligence-developed Software Bot to Improve Bowel Preparation and Colonoscopy Quality
Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Comparison of the efficacy and safety of sodium phosphate tablets and polyethylene glycol solution for bowel cleansing in healthy Korean adults.Yonsei medical journal · 2014Trial
- Randomized controlled trial comparing Moviprep® and Phosphoral® as bowel cleansing agents in patients undergoing colonoscopy.Techniques in coloproctology · 2014Trial
- A prospective study of bowel preparation for colonoscopy with polyethylene glycol-electrolyte solution versus sodium phosphate in Lynch syndrome: a randomized trial.Familial cancer · 2012Trial
- Comparative Colonisation Ability of Human Faecal Microbiome Transplantation Strategies in Murine Models.Microbial biotechnology · 2025Article
- Review
- Randomized Controlled Trial of Polyethylene Glycol versus Oral Sodium Phosphate for Bowel Preparation in Unsedated Colonoscopy.Gastroenterology research and practice · 2020Article
- Impact of bowel preparation type on the quality of colonoscopy: a multicenter community-based study.Journal of community hospital internal medicine perspectives · 2016Article
- Real-life conditions of use of sodium phosphate tablets for colon cleansing before colonoscopy.Endoscopy international open · 2015Article
- Achieving the best bowel preparation for colonoscopy.World journal of gastroenterology · 2014Review
- Sodium phosphate does not increase risk for acute kidney injury after routine colonoscopy, compared with polyethylene glycol.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2014Article
- Factors related to bowel cleansing failure before colonoscopy: Results of the PACOME study.United European gastroenterology journal · 2014Article
- Esophagogastroduodenoscopy-assisted bowel preparation for colonoscopy.World journal of gastrointestinal endoscopy · 2013Article
- Factors influencing quality of bowel preparation for colonoscopy.World journal of gastrointestinal endoscopy · 2013Article
- Polyethylene glycol and bisacodyl for colonoscopy: has the time arrived?Annals of gastroenterology · 2013Article
- Effectiveness of a simplified "patient friendly" split dose polyethylene glycol colonoscopy prep in Veterans Health Administration patients.Journal of interventional gastroenterology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundResults of meta-analyses of randomized trials comparing PEG and NaP are inconsistent and have not included trials comparing either or both preps to less traditional ones.
aimTo perform a meta-analysis by treatment arm.
methodsUsing MEDLINE and EMBASE, we identified English-language trials published from 1990 to 2008 that included PEG and/or NaP, and aggregated them by treatment arm into: 4 liter (L) PEG; 2 L PEG; split-dose PEG; two 45 ml doses of NaP +/- adjunctive medication; and NaP tablets. We compared prep quality and the proportion completing the prep.
resultsAmong 71 trials (patient N = 10,201), excellent prep quality was present in 34% (CI, 26-41%) for 4 L PEG alone; 39% (CI, 26-51%) for 2 L PEG; 37% (CI, 28-46%) for split-dose PEG; 42% (CI, 33-51%) for NaP solution; 44% (CI, 38-51%) for NaP with adjunctive meds; and 58% (CI, 49-67%) for NaP tablets. Patients receiving NaP were more likely to complete the prep (97% [CI, 96-98%] vs. 90% [CI, 87-92%] for 4L PEG alone); however, completion rates for 2L PEG (98%) and split dose PEG (95%) were similar to NaP.
conclusionsNaP tablets resulted in better prep quality and higher completion rates compared to other regimens. In comparisons limited by sample size, split dose PEG was not statistically different from NaP solution for completion rate or prep quality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.