Evidence map›Paper›PMID 21492329›Full record

SynthesisHPB : the official journal of the International Hepato Pancreato Biliary Association2011

Short- and long-term outcomes after laparoscopic and open hepatic resection: systematic review and meta-analysis.

Reza Mirnezami, Alexander H Mirnezami, Kandiah Chandrakumaran, Mohammad Abu Hilal, Neil W Pearce, John N Primrose, Robert P Sutcliffe

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  5. Economic analysis of open versus laparoscopic versus robotic hepatectomy: a systematic review and meta-analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2021
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reza MirnezamiDepartment of Surgery, Imperial Healthcare NHS Trust, London, UK.
Alexander H Mirnezami
Kandiah Chandrakumaran
Mohammad Abu Hilal
Neil W Pearce
John N Primrose
Robert P Sutcliffe

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic liver resection (LLR) is now considered a feasible alternative to open liver resection (OLR) in selected patients. Nevertheless studies comparing LLR and OLR are few and concerns remain about long-term oncological equivalence. The present study compares outcomes with LLR vs. OLR using meta-analytical methods.

methodsElectronic literature searches were conducted to identify studies comparing LLR and OLR. Short-term outcomes evaluated included operating time, blood loss, length of hospital stay, peri-operative morbidity and resection margin status. Longer-term outcomes included local and distant recurrence, and overall (OS) and disease-free survival (DFS). Meta-analyses were performed using the Mantel-Haenszel method and Cohen's d method, with results expressed as odds ratio (OR) or standardized mean difference (SMD), respectively, with 95% confidence intervals (CI).

resultsTwenty-six studies met the inclusion criteria with a population of 1678 patients. LLR resulted in longer operating time, but reduced blood loss, portal clamp time, overall and liver-specific complications, ileus and length of stay. No difference was found between LLR and OLR for oncological outcomes. DISCUSSION: LLR has short-term advantages and seemingly equivalent long-term outcomes and can be considered a feasible alternative to open surgery in experienced hands.

Indexed as

LaparoscopyDisease-Free SurvivalHepatectomyHospital CostsHumansLiver DiseasesLiver NeoplasmsOdds RatioPostoperative ComplicationsRecurrenceRisk AssessmentRisk FactorsTime FactorsTreatment Outcome

Identifiers

PMID21492329
PMCPMC3093641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.