ArticleClinical oral implants research2012
Influence of topography and hydrophilicity on initial oral biofilm formation on microstructured titanium surfaces in vitro.
Article in Clinical oral implants research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 93 citations in OpenAlex.
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- Novel Antibacterial Resin Coating for Dental Provisional Crowns to Suppress Biofilms and Inhibit Secondary Caries.Coatings (Basel, Switzerland) · 2024Article
- The Oral Microbiome of Peri-Implant Health and Disease: A Narrative Review.Dentistry journal · 2024Review
- Amorphous TiOBiomedical materials (Bristol, England) · 2024Article
- Impact of surface characteristics on the peri-implant microbiome in health and disease.Journal of periodontology · 2024Article
- Nanotopography and oral bacterial adhesion on titanium surfaces: in vitro and in vivo studies.Brazilian oral research · 2024Article
- Zwitterionic coating assisted by dopamine with metal-phenolic networks loaded on titanium with improved biocompatibility and antibacterial property for artificial heart.Frontiers in bioengineering and biotechnology · 2023Article
- Novel Giomers Incorporated with Antibacterial Quaternary Ammonium Monomers to Inhibit Secondary Caries.Pathogens (Basel, Switzerland) · 2022Article
- Effect of a Nanostructured Titanium Surface on Gingival Cell Adhesion, Viability and Properties againstMaterials (Basel, Switzerland) · 2021Article
- The Impact of Dental Implant Surface Modifications on Osseointegration and Biofilm Formation.Journal of clinical medicine · 2021Review
- Ways to control harmful biofilms: prevention, inhibition, and eradication.Critical reviews in microbiology · 2021Review
- Mechano-bactericidal actions of nanostructured surfaces.Nature reviews. Microbiology · 2021Review
- Effects of Surface Modification on Adsorption Behavior of Cell and Protein on Titanium Surface by Using Quartz Crystal Microbalance System.Materials (Basel, Switzerland) · 2020Article
- Decontamination of Ti Oxide Surfaces by Using Ultraviolet Light: Hg-Vapor vs. LED-Based Irradiation.Antibiotics (Basel, Switzerland) · 2020Article
- Effects of Plasma Treatment on the Bioactivity of Alkali-Treated Ceria-Stabilised Zirconia/Alumina Nanocomposite (NANOZR).International journal of molecular sciences · 2020Article
- Biological characterization of surface-treated dental implant materials in contact with mammalian host and bacterial cells: titaniumRSC advances · 2019Article
- Monitoring of biofilms grown on differentially structured metallic surfaces using confocal laser scanning microscopy.Engineering in life sciences · 2019Article
- Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains.BioMed research international · 2019Article
- Antibiofilm peptides against biofilms on titanium and hydroxyapatite surfaces.Bioactive materials · 2018Article
- Effects of low-frequency ultrasound treatment of titanium surface roughness on osteoblast phenotype and maturation.Clinical oral implants research · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
objectivesThe aim of this study was to analyse the influence of the microtopography and hydrophilicity of titanium (Ti) substrates on initial oral biofilm formation. MATERIALS AND
methodsNine bacterial species belonging to the normal oral microbiota, including: Aggregatibacter actinomycetemcomitans, Actinomyces israelii, Campylobacter rectus, Eikenella corrodens, Fusobacterium nucleatum, Parvimonas micra, Porphyromonas gingivalis, Prevotella intermedia, and Streptococcus sanguinis were tested on Ti surfaces: pretreatment (PT [R(a) <0.2 μm]), acid-etched (A [R(a) <0.8 μm]), A modified to be hydrophilic (modA), sand-blasted/acid-etched (SLA [R(a) =4 μm]), and hydrophilic SLA (modSLA). Disks were incubated for 24 h in anaerobic conditions using a normal culture medium (CM) or human saliva (HS). The total counts of bacteria and the proportion of each bacterial species were analysed by checkerboard DNA-DNA hybridization.
resultsHigher counts of bacteria were observed on all surfaces incubated with CM compared with the samples incubated with HS. PT, SLA, and modSLA exhibited higher numbers of attached bacteria in CM, whereas SLA and modSLA had a significant increase in bacterial adhesion in HS. The proportion of the species in the initial biofilms was also influenced by the surface properties and the media used: SLA and modSLA increased the proportion of species like A. actinomycetemcomitans and S. sanguinis in both media, while the adhesion of A. israelii and P. gingivalis on the same surfaces was affected in the presence of saliva.
conclusionsThe initial biofilm formation and composition were affected by the microtopography and hydrophilicity of the surface and by the media used.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.