Evidence map›Paper›PMID 21492066›Full record

Trial reportActa oto-laryngologica2011

Early self-care rehabilitation of head and neck cancer patients.

Alexander Ahlberg, Therese Engström, Polymnia Nikolaidis, Karin Gunnarsson, Hemming Johansson, Lena Sharp, Göran Laurell

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in Acta oto-laryngologica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05246891 (Rehabilitation Nursing Program in Otolaryngology), which is not on this map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05246891 completednot on this mapstarted 2018, after this paper: background citation

Rehabilitation Nursing Program in Otolaryngology

TypeobservationalSponsorUniversity of ÉvoraRan2018 to 2020Enrolled151ConditionsRehabilitation, Neck Cancer, Otorhinolaryngologic NeoplasmsArmsrehabilitation nursing
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury?Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Trial
  6. Trial
  7. Prophylactic exercises among head and neck cancer patients during and after swallowing sparing intensity modulated radiation: adherence and exercise performance levels of a 12-week guided home-based program.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Trial
  8. Trial
  9. Trial
  10. Two-year results of a prospective preventive swallowing rehabilitation trial in patients treated with chemoradiation for advanced head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2014
    Trial
  11. Trial
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Interventions to improve quality of life in patients with head and neck cancers receiving radiation therapy: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  18. Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alexander AhlbergDepartment of Otolaryngology, Karolinska University Hospital, Stockholm, Sweden. alexander.ahlberg@karolinska.se
Therese Engström
Polymnia Nikolaidis
Karin Gunnarsson
Hemming Johansson
Lena Sharp
Göran Laurell
Karolinska University Hospital · SEKarolinska Institutet · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

conclusionsNo positive effects of early preventive rehabilitation could be identified. The results do not contradict the proposition that rehabilitation based on self-care can be effective but it is important to establish evidence-based training programs and identify proper instruments for selection of patients and evaluation of intervention.

objectivesPatients with head and neck cancer suffer from functional impairments due to intense treatment. In this study, we investigated the effectiveness of an experimental early preventive rehabilitation using hard, objective end points in a nonselective, longitudinal, prospective cohort study.

methodsIn all, 190 patients were included in the program and received instructions for training before the start of treatment with the aim of reducing swallowing problems and reducing mouth opening and stiffness in the neck. A control group of 184 patients was recruited.

resultsThere was no difference in weight loss and 2-year survival between the two groups. No positive effects concerning functional impairments were found in patient-reported outcome measures.

Indexed as

AgedDeglutitionDeglutition DisordersExercise TherapyFemaleHead and Neck NeoplasmsHumansLongitudinal StudiesMaleMiddle AgedNeck PainProspective StudiesQuality of LifeRadiotherapySelf CareSpeech Disorders

Identifiers

PMID21492066
PMCPMC3082166
OpenAlexW2148253870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.