ArticlePharmaceutical research2011
The BCS, BDDCS, and regulatory guidances.
Article in Pharmaceutical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach.British journal of clinical pharmacology · 2016Trial
- Comparative Hydrophobicity, Solubility, and Metabolic Stability of 4(1ACS medicinal chemistry letters · 2025Article
- Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report.Molecular pharmaceutics · 2024Review
- Chemical Reactivity and Optical and Pharmacokinetics Studies of 14 Multikinase Inhibitors and Their Docking Interactions Toward ACK1 for Precision Oncology.Frontiers in chemistry · 2022Article
- An Overview on Dietary Polyphenols and Their Biopharmaceutical Classification System (BCS).International journal of molecular sciences · 2021Review
- ICH Guideline for Biopharmaceutics Classification System-Based Biowaiver (M9): Toward Harmonization in Latin American Countries.Pharmaceutics · 2021Article
- Can BDDCS illuminate targets in drug design?Drug discovery today · 2019Review
- Classification of WHO Essential Oral Medicines for Children Applying a Provisional Pediatric Biopharmaceutics Classification System.Pharmaceutics · 2019Article
- Drug Disposition Classification Systems in Discovery and Development: A Comparative Review of the BDDCS, ECCS and ECCCS Concepts.Pharmaceutical research · 2016Review
- BCS Biowaivers: Similarities and Differences Among EMA, FDA, and WHO Requirements.The AAPS journal · 2016Review
- BDDCS Predictions, Self-Correcting Aspects of BDDCS Assignments, BDDCS Assignment Corrections, and Classification for more than 175 Additional Drugs.The AAPS journal · 2016Review
- Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS).Pharmaceutical research · 2015Article
- Predicting the extent of metabolism using in vitro permeability rate measurements and in silico permeability rate predictions.Molecular pharmaceutics · 2015Article
- Experimental and theoretical studies on the molecular properties of ciprofloxacin, norfloxacin, pefloxacin, sparfloxacin, and gatifloxacin in determining bioavailability.Journal of biological physics · 2014Article
- Distinguishing between the permeability relationships with absorption and metabolism to improve BCS and BDDCS predictions in early drug discovery.Molecular pharmaceutics · 2014Article
- The use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.Pharmaceutical research · 2014Article
- How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion.Frontiers in pharmacology · 2014Review
- Drug discovery and regulatory considerations for improving in silico and in vitro predictions that use Caco-2 as a surrogate for human intestinal permeability measurements.The AAPS journal · 2013Article
- Comparison of the permeability of metoprolol and labetalol in rat, mouse, and Caco-2 cells: use as a reference standard for BCS classification.Molecular pharmaceutics · 2013Article
- The role of BCS (biopharmaceutics classification system) and BDDCS (biopharmaceutics drug disposition classification system) in drug development.Journal of pharmaceutical sciences · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
21491148What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.