Evidence map›Paper›PMID 21491140›Full record

ReviewDer Anaesthesist2011

[Cancer breakthrough pain. Indications for rapidly effective opioids].

J Kessler, H J Bardenheuer

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Anaesthesist, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Fentanyl buccal tablet for breakthrough cancer pain in clinical practice: results of the non-interventional prospective study ErkentNIS.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

J KesslerKlinik für Anaesthesiologie, Zentrum für Schmerztherapie und Palliativmedizin, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 131, Heidelberg, Germany. jens.kessler@med.uni-heidelberg.de
H J Bardenheuer
Heidelberg University · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmacotherapy of tumor pain has two main aims: to deliver an adequate basic analgesia using long-term retarded opioid medication and an effective treatment of tumor breakthrough pain using rapidly effective non-retarded opioids. Breakthrough pain is characterized by a sudden onset and rapid increase in the pain level and should be treated with correspondingly rapidly effective opioids. The pharmacological characteristics of previously available and routinely prescribed non-retarded opioids do not always correspond in oral galenics to the demands resulting from the definition of tumor breakthrough pain. As alternatives to these substances five different rapidly effective fentanyl preparations are now available for transmucosal administration.

Indexed as

Pain MeasurementAdministration, IntranasalAdministration, SublingualAdministration, TopicalAerosolsAnalgesics, OpioidBreakthrough PainDelayed-Action PreparationsFentanylHumansNeoplasmsAerosolsAnalgesics, OpioidDelayed-Action PreparationsFentanyl

Identifiers

PMID21491140
OpenAlexW2408983553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.