ArticleJournal of visualized experiments : JoVE2011
Evisceration of mouse vitreous and retina for proteomic analyses.
Article in Journal of visualized experiments : JoVE, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
- Principles of resident tissue macrophages revealed by the eye.Advances in immunology · 2026Review
- Biochemical Study of Bilberry Extract Potential in Preventing Retinal Damage in Rat Model of Diabetes Induced by Streptozotocin/Nicotinamide.Life (Basel, Switzerland) · 2025Article
- Vitreous Fibrillar Structure and Interfibrillar Composition in Adult Mice.Investigative ophthalmology & visual science · 2025Article
- Retina Phantom Model for Hyperspectral Imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- 5' Transgenes drive leaky expression of 3' transgenes in Cre-inducible bi-cistronic vectors.Molecular therapy. Methods & clinical development · 2024Article
- Investigation of Cas9 antibodies in the human eye.Nature communications · 2022Article
- Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa.JCI insight · 2021Article
- Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.JCI insight · 2021Article
- Retrobulbar administration of purified anti-nerve growth factor in developing rats induces structural and biochemical changes in the retina and cornea.International journal of ophthalmology · 2021Article
- Intravitreal Injection of Liposomes Loaded with a Histone Deacetylase Inhibitor Promotes Retinal Ganglion Cell Survival in a Mouse Model of Optic Nerve Crush.International journal of molecular sciences · 2020Article
- Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition.Investigative ophthalmology & visual science · 2020Article
- Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration.EBioMedicine · 2020Article
- Interleukin 22 ameliorates neuropathology and protects from central nervous system autoimmunity.Journal of autoimmunity · 2019Article
- Investigations Into Bioenergetic Neuroprotection of Cone Photoreceptors: Relevance to Retinitis Pigmentosa.Frontiers in neuroscience · 2019Article
- Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface.Free radical biology & medicine · 2018Article
- Liquid Biopsy of Vitreous Reveals an Abundant Vesicle Population Consistent With the Size and Morphology of Exosomes.Translational vision science & technology · 2018Article
- Dissection of Human Retina and RPE-Choroid for Proteomic Analysis.Journal of visualized experiments : JoVE · 2017Article
- Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis.Investigative ophthalmology & visual science · 2016Article
- Retinal pigment epithelial cell necroptosis in response to sodium iodate.Cell death discovery · 2016Article
- NGF Expression in Reelin-Deprived Retinal Cells: A Potential Neuroprotective Effect.Neuromolecular medicine · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
While the mouse retina has emerged as an important genetic model for inherited retinal disease, the mouse vitreous remains to be explored. The vitreous is a highly aqueous extracellular matrix overlying the retina where intraocular as well as extraocular proteins accumulate during disease.(1-3) Abnormal interactions between vitreous and retina underlie several diseases such as retinal detachment, proliferative diabetic retinopathy, uveitis, and proliferative vitreoretinopathy.(1,4) The relative mouse vitreous volume is significantly smaller than the human vitreous (Figure 1), since the mouse lens occupies nearly 75% of its eye.(5) This has made biochemical studies of mouse vitreous challenging. In this video article, we present a technique to dissect and isolate the mouse vitreous from the retina, which will allow use of transgenic mouse models to more clearly define the role of this extracellular matrix in the development of vitreoretinal diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.