Evidence map›Paper›PMID 21489289›Full record

ReviewMolecular cancer2011

The functional role of long non-coding RNA in human carcinomas.

Ewan A Gibb, Carolyn J Brown, Wan L Lam

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 937 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
937citing papers in PubMed, 3 pooled it
31.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

937 citing papers in PubMed, 3 syntheses or guidelines pooled it, 1,661 citations in OpenAlex.

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  20. The translatome of glioblastoma.Molecular oncology · 2025
    Article

877 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ewan A GibbBritish Columbia Cancer Agency Research Centre, Vancouver, Canada. egibb@bccrc.ca
Carolyn J Brown
Wan L Lam
BC Cancer Agency · CAUniversity of British Columbia · CA

Funding

Novel Reagents and New Biomarkers for Lung CancerU01CA084971 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GAZDAR, ADI F. · 1999 to 2009
$4.5M
Canadian Institutes of Health Research MOP 13690Canadian Institutes of Health Research MOP 77903Canadian Institutes of Health Research MOP 86731NCI NIH HHS 5U01 CA84971-10
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however the biological functions of the vast majority remain unknown. Recently, evidence has begun to accumulate describing the molecular mechanisms by which these RNA species function, providing insight into the functional roles they may play in tumorigenesis. In this review, we highlight the emerging functional role of lncRNAs in human cancer.

Indexed as

CarcinomaCell Transformation, NeoplasticGene Expression Regulation, NeoplasticHumansMicroRNAsRNA, UntranslatedSignal TransductionMicroRNAsRNA, Untranslated

Identifiers

PMID21489289
PMCPMC3098824
OpenAlexW2150695488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.