Evidence map›Paper›PMID 21488717›Full record

Trial reportDiabetes technology & therapeutics2011

Baseline predictors of A1C reduction in adults using sensor-augmented pump therapy or multiple daily injection therapy: the STAR 3 experience.

John B Buse, George Dailey, Andrew A Ahmann, Richard M Bergenstal, Jennifer B Green, Tim Peoples, Robert J Tanenberg, Qingqing Yang

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Diabetes technology & therapeutics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Continuous Glucose Monitoring Systems: A Review.Diagnostics (Basel, Switzerland) · 2013
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

John B BuseDivision of Endocrinology and Metabolism, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA. jbuse@med.unc.edu
George Dailey
Andrew A Ahmann
Richard M Bergenstal
Jennifer B Green
Tim Peoples
Robert J Tanenberg
Qingqing Yang
Medtronic (Ireland) · IEDuke Medical Center · USEast Carolina University · USOregon Health & Science University · USPark Nicollet Clinic · USScripps Clinic · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBaseline characteristics from the adult cohort of a randomized controlled trial comparing sensor-augmented pump (SAP) and multiple daily injection (MDI) therapy were analyzed for significant relationships with -0.5% A1C change at 1 year of therapy without incidence of severe hypoglycemia (defined as A1C benefit).

methodsBaseline characteristics were compared with A1C benefit. Statistically significant predictors were analyzed further to determine appropriate cutpoints of relative A1C benefit.

resultsBaseline A1C ≥9.1%, age at randomization ≥36 years, and age at diabetes diagnosis of ≥17 years were associated with a greater SAP benefit relative to MDI than other cutpoints.

conclusionsPeople with type 1 diabetes who had a high A1C and who were older at diagnosis and older at randomization experienced the most benefit from SAP therapy.

Indexed as

Insulin Infusion SystemsAdolescentAdultAgedAge FactorsChildCohort StudiesDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansHyperglycemiaHypoglycemic AgentsInsulinMaleMaterials TestingGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulin

Identifiers

PMID21488717
PMCPMC3101919
OpenAlexW2063063478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.