ArticleLangmuir : the ACS journal of surfaces and colloids2011
Effect of the peptide secondary structure on the peptide amphiphile supramolecular structure and interactions.
Article in Langmuir : the ACS journal of surfaces and colloids, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Programmable Electrostatics in Charge-Patterned Polypeptoid Micelles Probed by Small-Angle Neutron Scattering.Macromolecules · 2026Article
- Synthetic and Computational Design Insights toward Mimicking Protein Binding of Phosphate.Bioconjugate chemistry · 2024Article
- Investigation on the self-assembly of the NFL-TBS.40-63 peptide and its interaction with gold nanoparticles as a delivery agent for glioblastoma.International journal of pharmaceutics: X · 2022Article
- Self-assembling peptides-based nano-cargos for targeted chemotherapy and immunotherapy of tumors: recent developments, challenges, and future perspectives.Drug delivery · 2022Review
- Intrinsic Fluorescence in Peptide Amphiphile Micelles with Protein-Inspired Phosphate Sensing.Biomacromolecules · 2022Article
- Mapping the Morphological Landscape of Oligomeric Di-block Peptide-Polymer Amphiphiles.Angewandte Chemie (International ed. in English) · 2022Article
- Transition of Nano-Architectures Through Self-Assembly of Lipidated βFrontiers in chemistry · 2020Article
- Chronic inflammation deteriorates structure and function of collagen fibril in rat temporomandibular joint disc.International journal of oral science · 2019Article
- Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis.Journal of visualized experiments : JoVE · 2017Article
- Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation.Bioconjugate chemistry · 2017Article
- Self-assembling peptide-based building blocks in medical applications.Advanced drug delivery reviews · 2017Review
- Monocyte-targeting supramolecular micellar assemblies: a molecular diagnostic tool for atherosclerosis.Advanced healthcare materials · 2015Article
- Enhanced cellular entry and efficacy of tat conjugates by rational design of the auxiliary segment.Molecular pharmaceutics · 2014Article
- Article
- Fine-tuning the pH trigger of self-assembly.Journal of the American Chemical Society · 2012Article
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Authors and funding
6 authors.
Funding
Abstract
Bottom-up fabrication of self-assembled nanomaterials requires control over forces and interactions between building blocks. We report here on the formation and architecture of supramolecular structures constructed from two different peptide amphiphiles. Inclusion of four alanines between a 16-mer peptide and a 16 carbon long aliphatic tail resulted in a secondary structure shift of the peptide headgroups from α helices to β sheets. A concomitant shift in self-assembled morphology from nanoribbons to core-shell worm-like micelles was observed by cryogenic transmission electron microscopy (cryo-TEM) and atomic force microscopy (AFM). In the presence of divalent magnesium ions, these a priori formed supramolecular structures interacted in distinct manners, highlighting the importance of peptide amphiphile design in self-assembly.
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