ArticleMuscle & nerve2011
Changes in muscle T2 and tissue damage after downhill running in mdx mice.
Article in Muscle & nerve, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using MRI to quantify skeletal muscle pathology in Duchenne muscular dystrophy: A systematic mapping review.Muscle & nerve · 2021Pooled it
- Examination of effects of corticosteroids on skeletal muscles of boys with DMD using MRI and MRS.Neurology · 2014Trial
- MRI observations at return to play of clinically recovered hamstring injuries.British journal of sports medicine · 2014Trial
- Prediction of late-pregnancy pelvic floor dysfunction: a nomogram model based on proton density fat fraction and synthetic magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2026Article
- Quantitative MRI Assessment of Myotoxin-Induced Skeletal Muscle Damage of mdx Mice.Muscle & nerve · 2026Article
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- Distribution of MRI-derived T2 values as a biomarker for in vivo rapid screening of phenotype severity in mdx mice.PloS one · 2024Article
- Advanced quantitative magnetic resonance imaging of lower extremity muscle microtrauma after marathon: a mini review.Frontiers in sports and active living · 2024Review
- Magnetic resonance quantification of skeletal muscle lipid infiltration in a humanized mouse model of Duchenne muscular dystrophy.NMR in biomedicine · 2023Article
- Duchenne muscular dystrophy disease severity impacts skeletal muscle progenitor cells systemic delivery.Frontiers in physiology · 2023Article
- Effects of muscle damage onNMR in biomedicine · 2022Article
- The new challenge of "exercise + X″ therapy for Duchenne muscular dystrophy-Individualized identification of exercise tolerance and precise implementation of exercise intervention.Frontiers in physiology · 2022Review
- Case Report: Advanced Skeletal Muscle Imaging in S-Adenosylhomocysteine Hydrolase Deficiency and Further Insight Into Muscle Pathology.Frontiers in pediatrics · 2022Article
- Beneficial Role of Exercise in the Modulation ofAntioxidants (Basel, Switzerland) · 2021Review
- Exercise-induced muscle damage: multi-parametric MRI quantitative assessment.BMC musculoskeletal disorders · 2021Article
- Safety, feasibility, and efficacy of strengthening exercise in Duchenne muscular dystrophy.Muscle & nerve · 2021Article
- Mouse Models of Muscle Fibrosis.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Long-term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy.Journal of cachexia, sarcopenia and muscle · 2020Article
- MEF2c-Dependent Downregulation of Myocilin Mediates Cancer-Induced Muscle Wasting and Associates with Cachexia in Patients with Cancer.Cancer research · 2020Article
- Article
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Authors and funding
7 authors.
Funding
Abstract
introductionIn this study we compared the effects of downhill or horizontal treadmill running on the magnetic resonance imaging (MRI) transverse relaxation time constant (T(2)) in mdx mice.
methodsMice underwent either downhill (n = 11 mdx, n = 6 controls) or horizontal running (n = 9, mdx only) on a treadmill. MRI was conducted prior to exercise, immediately afterward (∽20 minutes), and then 24 and 48 hours after exercise.
resultsA higher percentage of pixels with elevated T(2) in the lower hindlimb muscles was observed in the mdx mice compared with controls both pre-exercise (P < 0.001) and at each time-point after downhill running (P < 0.05), but not with horizontal running. The medial compartment muscles appeared to be the most susceptible to increased T(2).
conclusionsDownhill running provides a stimulus for inducing acute changes in muscle T(2) in mdx mice. MRI is a non-invasive approach for examining acute muscle damage and recovery in multiple muscle groups simultaneously.
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