Evidence map›Paper›PMID 21488041›Full record

ArticleCurrent protocols in protein science2011

Preparation and analysis of glycan microarrays.

Jamie Heimburg-Molinaro, Xuezheng Song, David F Smith, Richard D Cummings

Open access · greenAbstract read
In one paragraph

Article in Current protocols in protein science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
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  10. Anti-schistosomal immunity to core xylose/fucose in N-glycans.Frontiers in molecular biosciences · 2023
    Article
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  19. Siglec Ligands.Cells · 2021
    Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jamie Heimburg-MolinaroThe Glycomics Center at Emory University School of Medicine, Atlanta, Georgia, USA.
Xuezheng Song
David F Smith
Richard D Cummings
Emory University · US

Funding

Structural Basis of Immune Recognition of Glycosylated AntigensU54GM062116 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI ORR, SALLY L · 2001 to 2010
$80.3M
Shotgun Glycomics: Linking Glycan Structure and FunctionR01GM085448 · NIGMS · EMORY UNIVERSITY · PI SMITH, DAVID FLETCHER · 2008 to 2011
$2.3M
NIGMS NIH HHS GM085448NIGMS NIH HHS GM62116NIGMS NIH HHS R01 GM085448NIGMS NIH HHS U54 GM062116
6 · The paper itself

Abstract

Determination of the binding specificity of glycan-binding proteins (GBPs), such as lectins, antibodies, and receptors, has traditionally been difficult and laborious. The advent of glycan microarrays has revolutionized the field of glycobiology by allowing simultaneous screening of a GBP for interactions with a large set of glycans in a single format. This unit describes the theory and method for production of two types of glycan microarrays (chemo/enzymatically synthesized and naturally derived), and their application to functional glycomics to explore glycan recognition by GBPs. These procedures are amenable to various types of arrays and a wide range of GBP samples.

Indexed as

GlycomicsLectinsMicroarray AnalysisModels, MolecularPolysaccharidesLectinsPolysaccharides

Identifiers

PMID21488041
PMCPMC3097418
OpenAlexW1523728762

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.