ArticleDiabetologia2011
No evidence of a higher 10 year period prevalence of diabetes among 77,885 twins compared with 215,264 singletons from the Danish birth cohorts 1910-1989.
Article in Diabetologia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight.Human molecular genetics · 2021Pooled it
- Metabolic signatures of birthweight in 18 288 adolescents and adults.International journal of epidemiology · 2016Pooled it
- Early Adoption of Digital Devices and Change in Loneliness Over 10 Years Among Late Middle-Aged and Older Adults: Longitudinal Cohort Study.JMIR formative research · 2026Article
- Moderating effects of educational inequality on education polygenic scores, attained education and dementia-risk relationships.SSM - population health · 2026Article
- Expanding the Danish Twin Registry into its Third Century: Secular Trends in Twin Births and Survival.Behavior genetics · 2026Article
- In Search of Environmental Factors Associated With Global Differences in Birth Weight and BMI.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- APOE Genotype, ApoE Plasma Levels, Lipid Metabolism, and Cognition in Monozygotic Twins with, at Risk of, and without Affective Disorders.Journal of clinical medicine · 2024Article
- Vitamin K1 Intake and Incident Diabetes in the Danish Diet, Cancer, and Health Study.The Journal of clinical endocrinology and metabolism · 2023Article
- Disentangling the relationship between bone turnover and glucose homeostasis: A prospective, population-based twin study.Bone reports · 2021Article
- Lifespans of Twins: Does Zygosity Matter?Genes · 2019Article
- Clinical Characteristics, Life Adversities and Personality Traits in Monozygotic Twins With, at Risk of and Without Affective Disorders.Frontiers in psychiatry · 2018Article
- Handgrip strength and its prognostic value for mortality in Moscow, Denmark, and England.PloS one · 2017Article
- Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau.BMC endocrine disorders · 2016Article
- Cognitive Functioning after Surgery in Middle-aged and Elderly Danish Twins.Anesthesiology · 2016Article
- Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2015Article
- Epigenetic signature of birth weight discordance in adult twins.BMC genomics · 2014Article
- Newborn infant characteristics and risk of future rheumatoid arthritis: a twin-control study.Rheumatology international · 2014Article
- Risk of metabolic syndrome and diabetes among young twins and singletons in Guinea-Bissau.Diabetes care · 2013Article
- A demonstration of the generalizability of twin-based research on antisocial behavior.Behavior genetics · 2013Article
- The Danish Twin Registry: linking surveys, national registers, and biological information.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisPrevious Danish twin studies have found a highly increased risk of precursors of type 2 diabetes as well as a higher prevalence of type 2 diabetes among twins compared with singletons. Likewise, small-scale studies of Danish twins have shown that monozygotic twins have a higher risk of developing precursors of type 2 diabetes compared with dizygotic twins. In the present register-based study, the 10 year period diabetes prevalence in Danish twins is compared with that in a random sample of Danish citizens. Furthermore, the 10 year period prevalence of diabetes in monozygotic twins is compared with that in dizygotic twins.
methodsThe study population consisted of twins (n = 77,885) identified in the Danish Twin Registry, and a 5% random sample (n = 215,264) from the birth cohorts 1910-1989. We identified diabetes patients by means of three nationwide Danish health registers.
resultsThe number of identified diabetes cases among males was 6,677 (6.24%) for singletons vs 2,271 (5.68%) for twins (difference = 0.56% [0.29-0.83%]). The number among females was 6,143 (5.67%) for singletons and 1,722 (4.54%) for twins (difference = 1.13% [0.88-0.38%]). Restriction to various birth cohorts, known zygosity and known type 2 diabetes did not alter the overall conclusions. The difference between monozygotic twins (males, 5.29%; females, 4.40%) and dizygotic twins (males, 5.77%; females, 4.63%) was non-significant. CONCLUSIONS/
interpretationDanish twins do not have an increased risk of developing diabetes compared with singletons, and the risk of diabetes among monozygotic twins does not differ from that of dizygotic twins.
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