ArticleSelf/nonself2010
Self and nonself recognition through C-type lectin receptor, Mincle.
Article in Self/nonself, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 46 citations in OpenAlex.
- Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study.Nature communications · 2025Observational
- Loss of Cullin 5 in myeloid cells protects against autoimmune neuroinflammation.Frontiers in immunology · 2025Article
- Article
- A mechanism of self-lipid endocytosis mediated by the receptor Mincle.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases.Journal of inflammation research · 2022Review
- Immunologic mechanism of fungal keratitis.International journal of ophthalmology · 2021Review
- Adjuvant activity ofHeliyon · 2020Article
- Myeloid C-Type Lectin Receptors in Tuberculosis and HIV Immunity: Insights Into Co-infection?Frontiers in cellular and infection microbiology · 2020Review
- Microglial Mincle receptor in the PVN contributes to sympathetic hyperactivity in acute myocardial infarction rat.Journal of cellular and molecular medicine · 2019Article
- Mincle in the innate immune response of mice fungal keratitis.International journal of ophthalmology · 2018Article
- Dectin-1-Syk-CARD9 Signaling Pathway in TB Immunity.Frontiers in immunology · 2018Review
- Signaling C-type lectin receptors in antimycobacterial immunity.PLoS pathogens · 2017Review
- The Interaction ofJournal of immunology (Baltimore, Md. : 1950) · 2017Article
- Mincle-Mediated Neutrophil Extracellular Trap Formation by Regulation of Autophagy.The Journal of infectious diseases · 2017Article
- C-type lectins: their network and roles in pathogen recognition and immunity.Histochemistry and cell biology · 2017Review
- Advanced Role of Neutrophils in Common Respiratory Diseases.Journal of immunology research · 2017Review
- Potential immunosuppressive effects of Escherichia coli O157:H7 experimental infection on the bovine host.BMC genomics · 2016Article
- Mincle suppresses Toll-like receptor 4 activation.Journal of leukocyte biology · 2016Article
- Dendritic cell immunoreceptor 1 alters neutrophil responses in the development of experimental colitis.BMC immunology · 2015Article
- Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy.Scientific reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mincle (also called as Clec4e or Clecsf9) is a C-type lectin receptor expressed in activated macrophages. Recently, we have reported that Mincle transduces the activation signals through ITAM-containing adaptor protein, FcRγ and induces the secretion of inflammatory cytokines. Furthermore, we and other groups have identified that Mincle recognizes a wide variety of ligands such as damaged cells, fungus, yeast and mycobacteria. These results indicate that Mincle acts as a multi-task danger receptor for both self and nonself ligands. This review summarizes the recent discoveries about the ligands and immunological roles of Mincle.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.