ArticleCase reports in gastroenterology2007
Pancreatitis following Olanzapine Therapy: A Report of Three Cases.
Article in Case reports in gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Olanzapine-induced acute necrotising pancreatitis leading to recurrent multiple organ dysfunction syndrome.General psychiatry · 2022Article
- Hyperbaric oxygen exposure alleviate metabolic side-effects of olanzapine treatment and is associated with Langerhans islet proliferation in rats.Pathology oncology research : POR · 2022Article
- Analysis of the clinical characteristics of olanzapine-induced acute pancreatitis.Therapeutic advances in psychopharmacology · 2022Review
- Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit?Annals of hematology · 2021Article
- Acute Necrotizing Pancreatitis following Long-Term Antipsychotic Use.Case reports in psychiatry · 2021Article
- Ever-increasing diversity of drug-induced pancreatitis.World journal of gastroenterology · 2020Review
- Successful clozapine rechallenge following recurrent clozapine-associated pancreatitis: a case report.BMC pharmacology & toxicology · 2020Article
- Universal Nature of Drug Treatment Responses in Drug-Tissue-Wide Model-Animal Experiments Using Tensor Decomposition-Based Unsupervised Feature Extraction.Frontiers in genetics · 2020Article
- Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths.JAMA psychiatry · 2019Article
- Atypical antipsychotics-induced metabolic syndrome and nonalcoholic fatty liver disease: a critical review.Neuropsychiatric disease and treatment · 2019Article
- Olanzapine-Induced Hypertriglyceridemia Resulting in Necrotizing Pancreatitis.ACG case reports journal · 2016Article
- Emphysematous pancreatitis predisposed by Olanzapine.Indian journal of anaesthesia · 2014Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextAtypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being treated with olanzapine. The mean age of the patients was 37.7 years (range 18-54 years, 2 female, 1 male). No alternative cause of acute pancreatitis was found in two of the three patients. In the remaining patient, olanzapine may have contributed to acute pancreatitis in the setting of hypertriglyceridemia. Olanzapine was discontinued in all instances. Over a mean follow-up of 14 months, one patient has had a relapsing course, but the remaining two patients have been symptom free without recurrence of acute pancreatitis.
conclusionsOur case series adds further support to the potential link between olanzapine use and acute pancreatitis. Close monitoring of metabolic parameters is suggested in patients treated with olanzapine. Alternative antipsychotic agents should be considered in patients at high risk for pancreatitis.
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