Evidence map›Paper›PMID 21487441›Full record

ArticleEuropean journal of human genetics : EJHG2011

Cancer GAMAdb: database of cancer genetic associations from meta-analyses and genome-wide association studies.

Sheri D Schully, Wei Yu, Victoria McCallum, Camilla B Benedicto, Linda M Dong, Anja Wulf, Melinda Clyne, Muin J Khoury

Abstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sheri D SchullyDivision of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA. schullys@mail.nih.gov
Wei Yu
Victoria McCallum
Camilla B Benedicto
Linda M Dong
Anja Wulf
Melinda Clyne
Muin J Khoury

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the field of cancer, genetic association studies are among the most active and well-funded research areas, and have produced hundreds of genetic associations, especially in the genome-wide association studies (GWAS) era. Knowledge synthesis of these discoveries is the first critical step in translating the rapidly emerging data from cancer genetic association research into potential applications for clinical practice. To facilitate the effort of translational research on cancer genetics, we have developed a continually updated database named Cancer Genome-wide Association and Meta Analyses database that contains key descriptive characteristics of each genetic association extracted from published GWAS and meta-analyses relevant to cancer risk. Here we describe the design and development of this tool with the aim of aiding the cancer research community to quickly obtain the current updated status in cancer genetic association studies.

Indexed as

Databases, GeneticGenome-Wide Association StudyMeta-Analysis as TopicHumansNeoplasms

Identifiers

PMID21487441
PMCPMC3172934

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.