ArticleInternational journal of obesity (2005)2012
Relationship between adiposity and admixture in African-American and Hispanic-American women.
Article in International journal of obesity (2005), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes.International journal of obesity (2005) · 2021Pooled it
- Trial
- Genetic ancestry in relation to the metabolic response to a US versus traditional Mexican diet: a randomized crossover feeding trial among women of Mexican descent.European journal of clinical nutrition · 2017Trial
- Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative.Nutrition journal · 2023Article
- Genetic admixture and cardiovascular disease risk in postmenopausal Hispanic women.International journal of cardiology · 2022Observational
- Admixture mapping of anthropometric traits in the Black Women's Health Study: evidence of a shared African ancestry component with birth weight and type 2 diabetes.Journal of human genetics · 2022Article
- Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL.Human molecular genetics · 2021Article
- Genetic underpinnings of regional adiposity distribution in African Americans: Assessments from the Jackson Heart Study.PloS one · 2021Article
- The role of country of birth, and genetic and self-identified ancestry, in obesity susceptibility among African and Hispanic Americans.The American journal of clinical nutrition · 2019Article
- The Prevalence of Helicobacter pylori in Estonian Bariatric Surgery Patients.International journal of molecular sciences · 2018Article
- Genetic admixture and body composition in Puerto Rican adults from the Boston Puerto Rican Osteoporosis Study.Journal of bone and mineral metabolism · 2017Article
- The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies.Frontiers in genetics · 2016Article
- Relationship of pain and ancestry in African American women.European journal of pain (London, England) · 2015Article
- Article
- Helicobacter pylori infection in obesity and its clinical outcome after bariatric surgery.World journal of gastroenterology · 2014Review
- Relationship between glaucoma and admixture in postmenopausal African American women.Ethnicity & disease · 2014Article
- Association of DXA-derived bone mineral density and fat mass with African ancestry.The Journal of clinical endocrinology and metabolism · 2013Article
- Relationship between hysterectomy and admixture in African American women.American journal of obstetrics and gynecology · 2013Article
- Genetic admixture and obesity: recent perspectives and future applications.Human heredity · 2013Review
- Relationship between diabetes risk and admixture in postmenopausal African-American and Hispanic-American women.Diabetologia · 2012Article
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11 authors.
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Abstract
objectiveThe objective of this study was to investigate whether differences in admixture in African-American (AFA) and Hispanic-American (HA) adult women are associated with adiposity and adipose distribution.
designThe proportion of European, sub-Saharan African and Amerindian admixture was estimated for AFA and HA women in the Women's Heath Initiative using 92 ancestry informative markers. Analyses assessed the relationship between admixture and adiposity indices. SUBJECTS: The subjects included 11 712 AFA and 5088 HA self-identified post-menopausal women.
resultsThere was a significant positive association between body mass index (BMI) and African admixture when BMI was considered as a continuous variable, and age, education, physical activity, parity, family income and smoking were included covariates (P<10(-4)). A dichotomous model (upper and lower BMI quartiles) showed that African admixture was associated with a high odds ratio (OR=3.27 (for 100% admixture compared with 0% admixture), 95% confidence interval 2.08-5.15). For HA, there was no association between BMI and admixture. In contrast, when waist-to-hip ratio (WHR) was used as a measure of adipose distribution, there was no significant association between WHR and admixture in AFA but there was a strong association in HA (P<10(-4); OR Amerindian admixture=5.93, confidence interval=3.52-9.97).
conclusionThese studies show that: (1) African admixture is associated with BMI in AFA women; (2) Amerindian admixture is associated with WHR but not BMI in HA women; and (3) it may be important to consider different measurements of adiposity and adipose distribution in different ethnic population groups.
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