ArticleInternational journal of obesity (2005)2012
Arterial stiffness, central blood pressure and body size in health and disease.
Article in International journal of obesity (2005), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Central-to-brachial blood pressure amplification in type 2 diabetes: a systematic review and meta-analysis.Journal of human hypertension · 2019Pooled it
- Investigating the Impact of Maternal Obesity on Disease Severity in a Mouse Model of Preeclampsia.Nutrients · 2025Article
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- Association of Nondiabetic Glucometabolic Status and Aortic Stiffness in Community Hypertension Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Does body mass index or waist-hip ratio correlate with arterial stiffness based on brachial-ankle pulse wave velocity in Chinese rural adults with hypertension?BMC cardiovascular disorders · 2021Article
- Changes in Central 24-h Ambulatory Blood Pressure and Hemodynamics 12 Months After Bariatric Surgery: the BARIHTA Study.Obesity surgery · 2020Observational
- Chronic Kidney Disease Modifies The Relationship Between Body Fat Distribution and Blood Pressure: A Cross-Sectional Analysis.International journal of nephrology and renovascular disease · 2020Article
- Importance of Sensitive Vascular Measurements for Evaluating Effects of Lifestyle in Premenopausal Women.Frontiers in cardiovascular medicine · 2020Article
- The effect of acute maximal exercise on postexercise hemodynamics and central arterial stiffness in obese and normal-weight individuals.Physiological reports · 2017Article
- Arterial Stiffness in Treated Hypertensive Patients With White-Coat Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Resting heart rate, physiological stress and disadvantage in Aboriginal and Torres Strait Islander Australians: analysis from a cross-sectional study.BMC cardiovascular disorders · 2016Article
- The relationship between weight, height and body mass index with hemodynamic parameters is not same in patients with and without chronic kidney disease.Clinical and experimental nephrology · 2016Article
- Is obesity predictive of cardiovascular dysfunction independent of cardiovascular risk factors?International journal of obesity (2005) · 2015Article
- Article
- More fuel in the obesity paradox debate.International journal of obesity (2005) · 2013Article
- Time-dependent alterations in rat macrovessels with type 1 diabetes.Experimental diabetes research · 2012Article
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBody size is associated with increased brachial systolic blood pressure (SBP) and aortic stiffness. The aims of this study were to determine the relationships between central SBP and body size (determined by body mass index (BMI), waist circumference and waist/hip ratio) in health and disease. We also sought to determine if aortic stiffness was correlated with body size, independent of BP.
methodsBMI, brachial BP and estimated central SBP (by SphygmoCor and radial P2) were recorded in controls (n=228), patients with diabetes (n=211), coronary artery disease (n=184) and end-stage kidney disease (n=68). Additional measures of waist circumference and arterial stiffness (aortic and brachial pulse wave velocity (PWV)) were recorded in a subgroup of 75 controls (aged 51 ± 12 years) who were carefully screened for factors affecting vascular function.
resultsBMI was associated with brachial (r=0.30; P<0.001) and central SBP (r=0.29; P<0.001) in the 228 controls, but not the patient populations (r<0.13; P>0.15 for all comparisons). In the control subgroup, waist circumference was also significantly correlated with brachial SBP (r=0.29; P=0.01), but not central SBP (r=0.22; P=0.07). Independent predictors of aortic PWV in the control subgroup were brachial SBP (β=0.43; P<0.001), age (β=0.37; P<0.001), waist circumference (β=0.39; P=0.02) and female sex (β=-0.24; P=0.03), but not BMI.
conclusionIn health, there are parallel increases in central and brachial SBP as BMI increases, but these relationships are not observed in the presence of chronic disease. Moreover, BP is a stronger correlate of arterial stiffness than body size.
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