Evidence map›Paper›PMID 21487116›Full record

ReviewJournal of dental research2011

Dynamics of salivary gland morphogenesis.

J Harunaga, J C Hsu, K M Yamada

Open access · greenAbstract readReview
In one paragraph

Review in Journal of dental research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
  2. Article
  3. The Mechanics of Building Functional Organs.Cold Spring Harbor perspectives in biology · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Cell signaling regulation in salivary gland development.Cellular and molecular life sciences : CMLS · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Voltage-dependent CaScientific reports · 2018
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J HarunagaLaboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bldg. 30, Room 426, 30 Convent Drive, MSC 4370, Bethesda, MD 20892-4370, USA.
J C Hsu
K M Yamada
National Institutes of Health · US

Funding

Craniofacial Developmental DynamicsZIADE000525 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI YAMADA, KENNETH · 2009 to 2025
$14.5M
Intramural NIH HHS ZIA DE000525
6 · The paper itself

Abstract

Salivary glands form during embryonic development by a complex process that creates compact, highly organized secretory organs with functions essential for oral health. The architecture of these glands is generated by branching morphogenesis, revealed by recent research to involve unexpectedly dynamic cell motility and novel regulatory pathways. Numerous growth factors, extracellular matrix molecules, gene regulatory pathways, and mechanical forces contribute to salivary gland morphogenesis, but local gene regulation and morphological changes appear to play particularly notable roles. Here we review these recent advances and their potential application to salivary gland tissue engineering.

Indexed as

AnimalsCell Adhesion MoleculesCell MovementEpithelial CellsExtracellular Matrix ProteinsFibronectinsGene Expression Regulation, DevelopmentalGrowth SubstancesHumansIntracellular Signaling Peptides and ProteinsMatrix Metalloproteinase 15Organogenesisrho-Associated KinasesSalivary GlandsTissue EngineeringTranscription FactorsCell Adhesion MoleculesExtracellular Matrix ProteinsFibronectinsGrowth SubstancesIntracellular Signaling Peptides and ProteinsMatrix Metalloproteinase 15rho-Associated KinasesTranscription Factors

Identifiers

PMID21487116
PMCPMC3318079
OpenAlexW2010123030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.