Evidence map›Paper›PMID 21486880›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2011

A secure protocol for protecting the identity of providers when disclosing data for disease surveillance.

Khaled El Emam, Jun Hu, Jay Mercer, Liam Peyton, Murat Kantarcioglu, Bradley Malin, David Buckeridge, Saeed Samet, Craig Earle

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  7. Article
  8. Fair compute loads enabled by blockchain: sharing models by alternating client and server roles.Journal of the American Medical Informatics Association : JAMIA · 2019
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  14. Clinical research informatics: a conceptual perspective.Journal of the American Medical Informatics Association : JAMIA · 2012
    Article
  15. Preserving Institutional Privacy in Distributed binary Logistic Regression.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2012
    Article
  16. Article
  17. Article
  18. Grid Binary LOgistic REgression (GLORE): building shared models without sharing data.Journal of the American Medical Informatics Association : JAMIA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khaled El EmamChildren's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada. kelemam@uottawa.ca
Jun Hu
Jay Mercer
Liam Peyton
Murat Kantarcioglu
Bradley Malin
David Buckeridge
Saeed Samet
Craig Earle

Funding

Technologies to Enable Privacy in Biomedical DatabanksR01LM009989 · NLM · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MALIN, BRADLEY A. · 2009 to 2014
$1.6M
CIHRNLM NIH HHS R01 LM009989NLM NIH HHS R01-LM009989
6 · The paper itself

Abstract

backgroundProviders have been reluctant to disclose patient data for public-health purposes. Even if patient privacy is ensured, the desire to protect provider confidentiality has been an important driver of this reluctance.

methodsSix requirements for a surveillance protocol were defined that satisfy the confidentiality needs of providers and ensure utility to public health. The authors developed a secure multi-party computation protocol using the Paillier cryptosystem to allow the disclosure of stratified case counts and denominators to meet these requirements. The authors evaluated the protocol in a simulated environment on its computation performance and ability to detect disease outbreak clusters.

resultsTheoretical and empirical assessments demonstrate that all requirements are met by the protocol. A system implementing the protocol scales linearly in terms of computation time as the number of providers is increased. The absolute time to perform the computations was 12.5 s for data from 3000 practices. This is acceptable performance, given that the reporting would normally be done at 24 h intervals. The accuracy of detection disease outbreak cluster was unchanged compared with a non-secure distributed surveillance protocol, with an F-score higher than 0.92 for outbreaks involving 500 or more cases.

conclusionThe protocol and associated software provide a practical method for providers to disclose patient data for sentinel, syndromic or other indicator-based surveillance while protecting patient privacy and the identity of individual providers.

Indexed as

Computer SecurityConfidentialityDisease NotificationPopulation SurveillanceDisease OutbreaksHumans

Identifiers

PMID21486880
PMCPMC3078664

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.