ArticleEnvironmental health perspectives2011
Polycyclic aromatic hydrocarbons-aromatic DNA adducts in cord blood and behavior scores in New York city children.
Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 6 of them syntheses that pooled it.
What it found
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Who cites it
61 citing papers in PubMed, 6 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- Association of prenatal and postnatal exposure to air pollution with clinically diagnosed attention deficit hyperactivity disorder: a systematic review.Frontiers in public health · 2024Pooled it
- Air pollution, depressive and anxiety disorders, and brain effects: A systematic review.Neurotoxicology · 2022Pooled it
- Impact of polycyclic aromatic hydrocarbon exposure on cognitive function and neurodegeneration in humans: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Effects of prenatal exposure to NOEnvironmental science and pollution research international · 2020Pooled it
- Association between exposure to polycyclic aromatic hydrocarbons and attention deficit hyperactivity disorder in children: a systematic review and meta-analysis.Environmental science and pollution research international · 2020Pooled it
- Perinatal Exposure to Environmental Endocrine Disruptors in the Emergence of Neurodevelopmental Psychiatric Diseases: A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- Developmental effects of exposures to environmental factors: the Polish Mother and Child Cohort Study.BioMed research international · 2013Trial
- Prenatal environmental risk for adolescent attention, thought, and substance use problems: A mixtures approach to coexposure and psychiatric comorbidities.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Air Pollution Exposure, Prefrontal Connectivity, and Emotional Behavior in Early Adolescence.Research report (Health Effects Institute) · 2025Article
- Prenatal polycyclic aromatic hydrocarbon exposure and neurodevelopment among children in Puerto Rico.Chemosphere · 2024Article
- Prenatal exposure to polycyclic aromatic hydrocarbons and executive functions at school age: Results from a combined cohort study.International journal of hygiene and environmental health · 2024Article
- Air pollution and age-dependent changes in emotional behavior across early adolescence in the U.S.Environmental research · 2024Article
- Ambient particulate matter (PMEnvironmental toxicology and pharmacology · 2023Article
- Prenatal exposure to air pollution and childhood internalizing problems: roles of shyness and anterior cingulate cortex activity.Journal of child psychology and psychiatry, and allied disciplines · 2023Article
- Prenatal exposure to polycyclic aromatic hydrocarbons is not associated with behavior problems in preschool and early school-aged children: A prospective multi-cohort study.Environmental research · 2023Article
- Air pollutants and attention deficit hyperactivity disorder medication administration in elementary schools.Biomedical reports · 2022Article
- Prenatal exposure to air pollution and maternal stress predict infant individual differences in reactivity and regulation and socioemotional development.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- Convergent neural correlates of prenatal exposure to air pollution and behavioral phenotypes of risk for internalizing and externalizing problems: Potential biological and cognitive pathways.Neuroscience and biobehavioral reviews · 2022Review
- Association among urinary polycyclic aromatic hydrocarbons and depression: a cross-sectional study from NHANES 2015-2016.Environmental science and pollution research international · 2022Article
- Residential greenness attenuated association of long-term air pollution exposure with elevated blood pressure: Findings from polluted areas in Northern China.Frontiers in public health · 2022Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAirborne polycyclic aromatic hydrocarbons (PAH) are widespread urban pollutants that can bind to DNA to form PAH-DNA adducts. Prenatal PAH exposure measured by personal monitoring has been linked to cognitive deficits in childhood in a prospective study conducted by the Columbia Center for Children's Environmental Health.
objectivesWe measured PAH-DNA and other bulky aromatic adducts in umbilical cord white blood cells using the 32P-postlabeling assay to determine the association between this molecular dosimeter and behavioral/attention problems in childhood.
methodsChildren born to nonsmoking African-American and Dominican women residing in New York City (NYC) were followed from in utero to 7-8 years of age. At two time points before 8 years of age (mean ages, 4.8 years and 7 years), child behavior was assessed using the Child Behavior Checklist (CBCL). To estimate and test the association between adducts and behavioral outcomes, both CBCL continuous raw scores and dichotomized T-scores were analyzed.
resultsHigher cord adducts were associated with higher symptom scores of Anxious/Depressed at 4.8 years and Attention Problems at 4.8 and 7 years, and with Diagnostic and Statistical Manual of Mental Disorders, 4th edition-oriented Anxiety Problems at 4.8 years.
conclusionsThese results suggest that PAH exposure, measured by DNA adducts, may adversely affect child behavior, potentially affecting school performance.
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