Evidence map›Paper›PMID 21484385›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2011

Quantitative imaging of 124I and 86Y with PET.

Mark Lubberink, Hans Herzog

Abstract readReview
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. An Overview of In Vitro Assays ofDiagnostics (Basel, Switzerland) · 2023
    Review
  6. Review
  7. Efficiency ofEJNMMI physics · 2022
    Article
  8. Positron Emission Intensity in the Decay ofMolecules (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Application Analysis ofInternational journal of nanomedicine · 2021
    Article
  15. Article
  16. Non-invasive Reporter Gene Imaging of Cell Therapies, including T Cells and Stem Cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Review
  17. Cerenkov luminescence and PET imaging ofPhysics in medicine and biology · 2020
    Article
  18. Article
  19. Article
  20. Preclinical Characterization ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mark LubberinkDepartment of Medical Physics and PET Centre, Uppsala University Hospital, Uppsala, Sweden. mark.lubberink@akademiska.se
Hans Herzog

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quantitative accuracy and image quality of positron emission tomography (PET) measurements with (124)I and (86)Y is affected by the prompt emission of gamma radiation and positrons in their decays, as well as the higher energy of the emitted positrons compared to those emitted by (18)F. PET scanners cannot distinguish between true coincidences, involving two 511-keV annihilation photons, and coincidences involving one annihilation photon and a prompt gamma, if the energy of this prompt gamma is within the energy window of the scanner. The current review deals with a number of aspects of the challenge this poses for quantitative PET imaging. First, the effect of prompt gamma coincidences on quantitative accuracy of PET images is discussed and a number of suggested corrections are described. Then, the effect of prompt gamma coincidences and the increased singles count rates due to gamma radiation on the count rate performance of PET is addressed, as well as possible improvements based on modification of the scanner's energy windows. Finally, the effect of positron energy on spatial resolution and recovery is assessed. The methods presented in this overview aim to overcome the challenges associated with the decay characteristics of (124)I and (86)Y. Careful application of the presented correction methods can allow for quantitatively accurate images with improved image contrast.

Indexed as

Iodine RadioisotopesYttrium RadioisotopesEquipment DesignEquipment Failure AnalysisGamma RaysImage EnhancementImaging, Three-DimensionalPhotonsPositron-Emission TomographyScattering, RadiationTomography, Emission-ComputedIodine RadioisotopesYttrium Radioisotopes

Identifiers

PMID21484385
PMCPMC3098993

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.