ArticleJournal of ophthalmic inflammation and infection2011
Central retinal artery occlusion in Wegener's granulomatosis: a diagnostic dilemma.
Article in Journal of ophthalmic inflammation and infection, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Retinal thickness and microvascular alterations observed by optical coherence tomography in antineutrophil cytoplasmic antibody-associated vasculitis: a cross-sectional study.Quantitative imaging in medicine and surgery · 2024Article
- Central Retinal Artery Occlusion: A Review of Pathophysiological Features and Management.Stroke (Hoboken, N.J.) · 2024Review
- ANCA-associated vasculitis presenting with progressive binocular manifestations: a case report and literature review.Frontiers in medicine · 2024Article
- Subclinical microvascular changes in ANCA-vasculitides: the role of optical coherence tomography angiography and nailfold capillaroscopy in the detection of disease-related damage.Orphanet journal of rare diseases · 2023Observational
- Conjunctivitis as the important indicator of pediatric granulomatosis with polyangiitis.SAGE open medical case reports · 2022Article
- Atypical Granulomatosis with Polyangiitis Presenting with Meibomitis, Scleritis, Uveitis and Papillary Bladder Tumor: A Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2021Article
- Case of Nocardia Cyriacigeorgica Infection of the Eye in a Granulomatosis With Polyangiitis Patient.Cureus · 2020Article
- Atypical painless vision loss in a patient with granulomatosis with polyangiitis.GMS ophthalmology cases · 2020Article
- Ocular Manifestations of Granulomatosis with Polyangiitis: A Review of the Literature.Ophthalmology and therapy · 2019Review
- Conjunctivitis as a manifestation of Wegener's Granulomatosis.Journal of current ophthalmology · 2018Article
- Simultaneous Unilateral Presentation of Three Different Ocular Manifestations of Granulomatosis with Polyangiitis.Journal of ophthalmic & vision researchArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report a case of central retinal artery occlusion (CRAO) in a patient with biopsy-verified Wegener's granulomatosis (WG) with positive C-ANCA.
methodsA 55-year-old woman presented with a 3-day history of acute painless bilateral loss of vision; she also complained of fever and weight loss. Examination showed a CRAO in the left eye and angiographically documented choroidal ischemia in both eyes.
resultsThe possibility of systemic vasculitis was not kept in mind until further studies were carried out; methylprednisolone pulse therapy was then started. Renal biopsy disclosed focal and segmental necrotizing vasculitis of the medium-sized arteries, supporting the diagnosis of WG, and cyclophosphamide pulse therapy was administered with gradual improvement, but there was no visual recovery.
conclusionCRAO as presenting manifestation of WG, in the context of retinal vasculitis, is very uncommon, but we should be aware of WG in the etiology of CRAO. This report shows the difficulty of diagnosing Wegener's granulomatosis; it requires a high index of suspicion, and we should obtain an accurate medical history and repeat serological and histopathological examinations. It emphasizes that inflammation of arteries leads to irreversible retinal infarction, and visual loss may occur.
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Registered trials
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