Evidence map›Paper›PMID 21483615›Full record

ArticleBiomedical optics express2011

Chemical visualization of individual chondrocytes in articular cartilage by attenuated-total-reflection Fourier Transform Infrared Microimaging.

Jianhua Yin, Yang Xia

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Biochemical similarity between cultured chondrocytes andBiotechnology reports (Amsterdam, Netherlands) · 2019
    Article
  3. Functional properties of chondrocytes and articular cartilage using optical imaging to scanning probe microscopy.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jianhua YinDepartment of Physics and Center for Biomedical Research, Oakland University, Rochester, MI 48309, USA.
Yang Xia
University of Rochester · US

Funding

Quantitative molecular imaging in articular cartilageR01AR045172 · NIAMS · OAKLAND UNIVERSITY · PI XIA, YANG · 1999 to 2009
$2.6M
Adaptability of Articular Cartilage to External Loading by Microscopic ImagingR01AR052353 · NIAMS · OAKLAND UNIVERSITY · PI XIA, YANG · 2008 to 2013
$2.1M
NIAMS NIH HHS R01 AR045172NIAMS NIH HHS R01 AR052353
6 · The paper itself

Abstract

Fourier transform infrared imaging (FTIRI) and the attenuated total reflection Fourier transform infrared microimaging (ATR-FTIRM) were used to study the chemical and structural distributions of cellular components surrounding individual chondrocytes in canine humeral cartilage, at 6.25µm pixel resolution in FTIRI and 1.56µm pixel resolution in ATR-FTIRM. The chemical and structural distributions of the cellular components in chondrocytes and tissue can be successfully imaged in high resolution ATR-FTIRM. One can also study the territorial matrix of fine collagen fibrils surrounding the individual chondrocytes by the polarization experiments using the absorption ratio of amide I to amide II bands.

Indexed as

(110.3080) Infrared imaging(120.6200) Spectrometers and spectroscopic instrumentation(170.1530) Cell analysis(170.3880) Medical and biological imaging(170.3890) Medical optics instrumentation(300.6340) Spectroscopy, infrared

Identifiers

PMID21483615
PMCPMC3072132
OpenAlexW1966873246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.