ArticleAging2011
The physiological roles of Sirt1 in skeletal muscle.
Article in Aging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 97 citations in OpenAlex.
- Exercise improves hypobaric hypoxia-induced skeletal muscle dysfunction via Sirt1-Mediated myotube and mitochondrial remodeling.Journal of advanced research · 2026Article
- Sirtuin 1 as an emerging exerkine in the aging process: unveiling its multifaceted biological roles.Biogerontology · 2026Review
- Emerging landscape of lncRNA-miRNA interactions as architects of gene expression patterns.Molecular biology reports · 2025Review
- Does Green Tea Ameliorate Obesity in Mice Kept at Thermoneutrality by Modulating Skeletal Muscle Metabolism?Cell biochemistry and function · 2025Article
- Dissimilar Effects of Selenite and Selenium Nanoparticles on Skeletal Muscle Development Unrelated to GPx1 Activity During Adolescence in Rats.Nutrients · 2025Article
- Article
- TRIM16 facilitates SIRT-1-dependent regulation of antioxidant response to alleviate age-related sarcopenia.Journal of cachexia, sarcopenia and muscle · 2024Article
- Piceatannol Upregulates SIRT1 Expression in Skeletal Muscle Cells and in Human Whole Blood: In Vitro Assay and a Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial.Life (Basel, Switzerland) · 2024Article
- SIRT1 activation attenuates palmitate induced apoptosis in CMolecular biology reports · 2024Article
- Estradiol as the Trigger of Sirtuin-1-Dependent Cell Signaling with a Potential Utility in Anti-Aging Therapies.International journal of molecular sciences · 2023Review
- Molecular hallmarks of long non-coding RNAs in aging and its significant effect on aging-associated diseases.Neural regeneration research · 2023Review
- Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1.Cancers · 2023Article
- Sex differences in muscle SIRT1 and SIRT3 and exercise + weight loss effects on muscle sirtuins.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- Bioactive Components in Whole Grains for the Regulation of Skeletal Muscle Function.Foods (Basel, Switzerland) · 2022Review
- CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice.GeroScience · 2022Article
- Identification of the shared gene signatures and pathways between sarcopenia and type 2 diabetes mellitus.PloS one · 2022Article
- A Comprehensive Review: Molecular and Genetic Background of Indirect Inguinal Hernias.Visceral medicine · 2021Review
- Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.International journal of molecular sciences · 2021Article
- Curcumin and Resveratrol Improve Muscle Function and Structure through Attenuation of Proteolytic Markers in Experimental Cancer-Induced Cachexia.Molecules (Basel, Switzerland) · 2021Article
- Sirtuin 1 is not required for contraction-stimulated glucose uptake in mouse skeletal muscle.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal muscle aging is associated with increased inflammation and oxidative stress, a decrease in the ability to rebuild muscle after injury and in response to exercise. In this perspective, we discuss the mechanisms regulating Sirt1 activity and expression in skeletal muscles, emphasizing their implications in muscle physiology and the impairment of muscle function with age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.