ArticleThe Journal of biological chemistry2011
A novel transcription factor, ERD15 (Early Responsive to Dehydration 15), connects endoplasmic reticulum stress with an osmotic stress-induced cell death signal.
Article in The Journal of biological chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cell Death Signaling From Endoplasmic Reticulum Stress: Plant-Specific and Conserved Features.Frontiers in plant science · 2022Pooled it
- The Wheat NucleoredoxinPlants (Basel, Switzerland) · 2026Article
- Expansion and diversification of the Glycine max (Gm) ERD15-like subfamily of the PAM2-like superfamily.Planta · 2024Article
- Integrating GWAS with a gene co-expression network better prioritizes candidate genes associated with root metaxylem phenes in maize.The plant genome · 2024Article
- A conserved oomycete effector RxLR23 triggers plant defense responses by targeting ERD15La to release NbNAC68.Nature communications · 2024Article
- Characteristics analysis ofPlant signaling & behavior · 2023Article
- Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy-Induced Necrosis.Cancer research · 2023Article
- Comparative Analysis of Antioxidant System and Salt-Stress Tolerance in Two Hibiscus Cultivars Exposed to NaCl Toxicity.Plants (Basel, Switzerland) · 2023Article
- Genome-Wide Characterization and Function Analysis ofInternational journal of molecular sciences · 2022Article
- Genome-Wide Prediction and Analysis ofInternational journal of molecular sciences · 2022Article
- Abiotic Stresses in Plants and Their Markers: A Practice View of Plant Stress Responses and Programmed Cell Death Mechanisms.Plants (Basel, Switzerland) · 2022Review
- Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress.Plant physiology · 2021Article
- Senescence-AssociatedInternational journal of molecular sciences · 2021Review
- Natural variation in the promoter of GsERD15B affects salt tolerance in soybean.Plant biotechnology journal · 2021Article
- ABAS1 from soybean is a 1R-subtype MYB transcriptional repressor that enhances ABA sensitivity.Journal of experimental botany · 2020Article
- GmNAC81 Inversely Modulates Leaf Senescence and Drought Tolerance.Frontiers in genetics · 2020Article
- OXI1 and DAD Regulate Light-Induced Cell Death Antagonistically through Jasmonate and Salicylate Levels.Plant physiology · 2019Article
- RAMOSA1 ENHANCER LOCUS2-Mediated Transcriptional Repression Regulates Vegetative and Reproductive Architecture.Plant physiology · 2019Article
- Cloning and Expression Analysis ofIranian journal of biotechnology · 2018Article
- Age-related cataracts: Role of unfolded protein response, CaProgress in retinal and eye research · 2017Review
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As in all other eukaryotic organisms, endoplasmic reticulum (ER) stress triggers the evolutionarily conserved unfolded protein response in soybean, but it also communicates with other adaptive signaling responses, such as osmotic stress-induced and ER stress-induced programmed cell death. These two signaling pathways converge at the level of gene transcription to activate an integrated cascade that is mediated by N-rich proteins (NRPs). Here, we describe a novel transcription factor, GmERD15 (Glycine max Early Responsive to Dehydration 15), which is induced by ER stress and osmotic stress to activate the expression of NRP genes. GmERD15 was isolated because of its capacity to stably associate with the NRP-B promoter in yeast. It specifically binds to a 187-bp fragment of the NRP-B promoter in vitro and activates the transcription of a reporter gene in yeast. Furthermore, GmERD15 was found in both the cytoplasm and the nucleus, and a ChIP assay revealed that it binds to the NRP-B promoter in vivo. Expression of GmERD15 in soybean protoplasts activated the NRP-B promoter and induced expression of the NRP-B gene. Collectively, these results support the interpretation that GmERD15 functions as an upstream component of stress-induced NRP-B-mediated signaling to connect stress in the ER to an osmotic stress-induced cell death signal.
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