Evidence map›Paper›PMID 21482742›Full record

ReviewCold Spring Harbor perspectives in biology2011

Entry and exit mechanisms at the cis-face of the Golgi complex.

Andrés Lorente-Rodríguez, Charles Barlowe

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Sec17 (α-SNAP) and Sec18 (NSF) restrict membrane fusion to R-SNAREs, Q-SNAREs, and SM proteins from identical compartments.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Organization of the ER-Golgi interface for membrane traffic control.Nature reviews. Molecular cell biology · 2013
    Review
  20. Multi-step down-regulation of the secretory pathway in mitosis: a fresh perspective on protein trafficking.BioEssays : news and reviews in molecular, cellular and developmental biology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrés Lorente-RodríguezDepartment of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
Charles Barlowe

Funding

Mechanisms of COPII-Dependent TransportR37GM052549 · NIGMS · DARTMOUTH COLLEGE · PI BARLOWE, CHARLES K · 2007 to 2016
$5.3M
NIGMS NIH HHS R37 GM052549
6 · The paper itself

Abstract

Vesicular transport of protein and lipid cargo from the endoplasmic reticulum (ER) to cis-Golgi compartments depends on coat protein complexes, Rab GTPases, tethering factors, and membrane fusion catalysts. ER-derived vesicles deliver cargo to an ER-Golgi intermediate compartment (ERGIC) that then fuses with and/or matures into cis-Golgi compartments. The forward transport pathway to cis-Golgi compartments is balanced by a retrograde directed pathway that recycles transport machinery back to the ER. How trafficking through the ERGIC and cis-Golgi is coordinated to maintain organelle structure and function is poorly understood and highlights central questions regarding trafficking routes and organization of the early secretory pathway.

Indexed as

Secretory PathwayCOP-Coated VesiclesEndoplasmic ReticulumGolgi ApparatusMembrane FusionMembrane Fusion ProteinsModels, BiologicalProtein Structure, TertiaryVesicular Transport ProteinsMembrane Fusion Proteinstransport protein particle, TRAPPVesicular Transport Proteins

Identifiers

PMID21482742
PMCPMC3119910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.