ArticleBioconjugate chemistry2011
Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide.
Article in Bioconjugate chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- Recent advances in multimodal imaging of infections: research highlights using Nuclear-Optical imaging.European journal of nuclear medicine and molecular imaging · 2026Review
- Peptide Dendrimer-Based Antibacterial Agents: Synthesis and Applications.ACS infectious diseases · 2024Review
- A Truncated 14-Amino-Acid Myelin Protein-Zero-Targeting Peptide for Fluorescence-Guided Nerve-Preserving Surgery.Biomolecules · 2023Article
- Nerve Targeting via Myelin Protein Zero and the Impact of Dimerization on Binding Affinity.Molecules (Basel, Switzerland) · 2022Article
- (5E,7E)-4,5,6 Trihydroxy-3-(hydroxymethyl)tetrahydro-2H-pyran-2-ylheptadeca-5,7-dienoate fromBioinorganic chemistry and applications · 2022Article
- At the Bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer.Journal of leukocyte biology · 2021Review
- The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery.Biomolecules · 2021Article
- Emerging Fluorescent Molecular Tracers to Guide Intra-Operative Surgical Decision-Making.Frontiers in pharmacology · 2019Review
- Nuclear and Optical Bimodal Imaging Probes Using Sequential Assembly: A Perspective.Cancer biotherapy & radiopharmaceuticals · 2018Review
- CXCR4-directed theranostics in oncology and inflammation.Annals of nuclear medicine · 2018Review
- Bioorthogonally Applicable Fluorescence Deactivation Strategy for Receptor Kinetics Study and Theranostic Pretargeting Approaches.Chembiochem : a European journal of chemical biology · 2018Article
- Novel solid-phase strategy for the synthesis of ligand-targeted fluorescent-labelled chelating peptide conjugates as a theranostic tool for cancer.Beilstein journal of organic chemistry · 2018Article
- Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma.BMC cancer · 2017Article
- Potential of CXCR4/CXCL12 Chemokine Axis in Cancer Drug Delivery.Current pharmacology reports · 2016Article
- Structural characterization and in vivo evaluation of β-Hairpin peptidomimetics as specific CXCR4 imaging agents.Molecular pharmaceutics · 2015Article
- Bridged cyclams as imaging agents for chemokine receptor 4 (CXCR4).Nuclear medicine and biology · 2014Article
- The intricate role of CXCR4 in cancer.Advances in cancer research · 2014Review
- Bimodal imaging probes for combined PET and OI: recent developments and future directions for hybrid agent development.BioMed research international · 2014Review
- Comparison of (18)F-labeled CXCR4 antagonist peptides for PET imaging of CXCR4 expression.Molecular imaging and biology · 2013Article
- Multimodality imaging of CXCR4 in cancer: current status towards clinical translation.Current molecular medicine · 2013Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The antagonistic Ac-TZ14011 peptide, which binds to the chemokine receptor 4, has been labeled with a multifunctional single attachment point reagent that contains a DTPA chelate and a fluorescent dye with Cy5.5 spectral properties. Flow cytometry and confocal microscopy showed that the bimodal labeled peptide gave a specific receptor binding that is similar to monofunctionalized peptide derivatives. Therefore, the newly developed bimodal peptide derivative can be used in multimodal imaging applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.