Evidence map›Paper›PMID 21480242›Full record

ReviewJournal of surgical oncology2011

Translational/personalized medicine, pharmaco/surgico/radiogenomics, lymphatic spread of cancer, and medical ignoromes.

Marlys H Witte

Abstract readReview
In one paragraph

Review in Journal of surgical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Marlys H WitteDepartment of Surgery, University of Arizona College of Medicine, Tucson, Arizona 85724-5200, USA. grace@surgery.arizona.edu

Funding

BBB Tight Junctions During HIV-1 dementiaR01MH065151 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PERSIDSKY, YURI · 2002 to 2016
$5.9M
SHORT-TERM TRAINING STUDENTS IN HEALTH PROFESSIONAL SCHOT35HL007479 · NHLBI · UNIVERSITY OF ARIZONA · PI GEOFFREY C GURTNER, JAMES Kuang-Jan LIAO · 1985 to 2026
$4.4M
K-12 Virtual Clinical Research Center & Medical Ignorance Exploratorium: Phase I+R25RR022720 · NCRR · UNIVERSITY OF ARIZONA · PI WITTE, MARLYS HEARST · 2006 to 2011
$1.8M
NCRR NIH HHS 1R25RR022720NCRR NIH HHS R25 RR022720NHLBI NIH HHS T35 HL007479NHLBI NIH HHS T35HL07479NIMH NIH HHS R01 MH065151NIMH NIH HHS R01MH065151
6 · The paper itself

Abstract

In the elusive quest for "personalized" cancer treatments based on pharmacogenomics, diverse challenges must be overcome: questionable validity of "molecular models of life," obstacles to bidirectional translation of scientific advances from bench to bedside to community, and limitations of bioinformatics to recognize and deal with "ignoramics/ignoromes" (expanding unknowns in cancer biology, theranostics, and therapeutic choices). These considerations apply to lymphatic system functioning-lymphatic vessels, lymph, lymph nodes, and lymphocytes-in diseases like cancer.

Indexed as

GenomicsMolecular Targeted TherapyPrecision MedicineTranslational Research, BiomedicalHumansLymphatic MetastasisNeoplasmsPharmacogenetics

Identifiers

PMID21480242
PMCPMC4026306

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.