ReviewJournal of surgical oncology2011
Experimental models to study lymphatic and blood vascular metastasis.
Review in Journal of surgical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis.Angiogenesis · 2017Article
- Modeling pre-metastatic lymphvascular niche in the mouse ear sponge assay.Scientific reports · 2017Article
- Intravital Imaging Reveals Dynamics of Lymphangiogenesis and Valvulogenesis.Scientific reports · 2016Article
- Walking the Line: A Fibronectin Fiber-Guided Assay to Probe Early Steps of (Lymph)angiogenesis.PloS one · 2015Article
- Corneal lymphatic valve formation in relation to lymphangiogenesis.Investigative ophthalmology & visual science · 2014Article
- Protective effects of matrix metalloproteinase-12 following corneal injury.Journal of cell science · 2013Article
- [Proteome profiling for the identification of lung cancer signatures].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2012Article
- Conjunctival lymphatic response to corneal inflammation in mice.Journal of ophthalmology · 2012Article
- Watching lymphatic vessels grow by making them glow.Cell research · 2012Article
- Live imaging of newly formed lymphatic vessels in the cornea.Cell research · 2011Article
- Combined blockade of VEGFR-3 and VLA-1 markedly promotes high-risk corneal transplant survival.Investigative ophthalmology & visual science · 2011Article
- Increased lymphangiogenesis and hemangiogenesis in infant cornea.Lymphatic research and biology · 2011Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
As a model system for the understanding of human cancer, the mouse has proved immensely valuable. Indeed, studies of mouse models have helped to define the nature of cancer as a genetic disease and demonstrated the causal role of genetic events found in tumors. As an experimental platform, they have provided critical insight into the process of tumor metastasis in the lymphovascular system. Once viewed with skepticism, mouse models are now an integral arm of basic and clinical cancer research. The use of a genetically tractable organism that shares organ systems and an immense degree of genetic similarity to humans provides a means to examine multiple features of human disease. Mouse models enable development and testing of new approaches to disease prevention and treatment, identification of early diagnostic markers and novel therapeutic targets, and an understanding of the in vivo biology and genetics of tumor initiation, promotion, progression, and metastasis. This review summarizes recent mouse models for lymphangiogenesis and the process of lymphovascular metastasis, focusing on the use of the cornea as an experimental platform for lymphangiogenesis in inflammation and immunity, and on the use of molecular and viral vector mediated imaging and to identify and monitor lymph node metastases of prostate cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.