Evidence map›Paper›PMID 21480044›Full record

ArticleJournal of toxicology and environmental health. Part A2011

Fine particulate air pollution is associated with higher vulnerability to atrial fibrillation--the APACR study.

Duanping Liao, Michele L Shaffer, Fan He, Sol Rodriguez-Colon, Rongling Wu, Eric A Whitsel, Edward O Bixler, Wayne E Cascio

Abstract read
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Air Pollution-Induced Autonomic Modulation.Physiology (Bethesda, Md.) · 2020
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation.International journal of environmental research and public health · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Duanping LiaoDepartment of Public Health Sciences, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA. dliao@psu.edu
Michele L Shaffer
Fan He
Sol Rodriguez-Colon
Rongling Wu
Eric A Whitsel
Edward O Bixler
Wayne E Cascio

Funding

Air Pollution and Cardiac Risk: Mechanisms & Time-courseR01ES014010 · NIEHS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LIAO, DUANPING · 2007 to 2010
$1.1M
NIEHS NIH HHS 1 R01 ES014010NIEHS NIH HHS R01 ES014010
6 · The paper itself

Abstract

The acute effects and the time course of fine particulate pollution (PM₂.₅) on atrial fibrillation/flutter (AF) predictors, including P-wave duration, PR interval duration, and P-wave complexity, were investigated in a community-dwelling sample of 106 nonsmokers. Individual-level 24-h beat-to-beat electrocardiogram (ECG) data were visually examined. After identifying and removing artifacts and arrhythmic beats, the 30-min averages of the AF predictors were calculated. A personal PM₂.₅ monitor was used to measure individual-level, real-time PM₂.₅ exposures during the same 24-h period, and corresponding 30-min average PM₂.₅ concentration were calculated. Under a linear mixed-effects modeling framework, distributed lag models were used to estimate regression coefficients (βs) associating PM₂.₅ with AF predictors. Most of the adverse effects on AF predictors occurred within 1.5-2 h after PM₂.₅ exposure. The multivariable adjusted βs per 10-μg/m³ rise in PM₂.₅ at lag 1 and lag 2 were significantly associated with P-wave complexity. PM₂.₅ exposure was also significantly associated with prolonged PR duration at lag 3 and lag 4. Higher PM₂.₅ was found to be associated with increases in P-wave complexity and PR duration. Maximal effects were observed within 2 h. These findings suggest that PM₂.₅ adversely affects AF predictors; thus, PM₂.₅ may be indicative of greater susceptibility to AF.

Indexed as

Air PollutantsAir PollutionAtrial FibrillationElectrocardiographyFemaleHumansInhalation ExposureMaleMiddle AgedParticulate MatterPennsylvaniaAir PollutantsParticulate Matter

Identifiers

PMID21480044
PMCPMC3082849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.