Evidence map›Paper›PMID 21479956›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2011

Impaired renal function is associated with worse self-reported outcomes after kidney transplantation.

Luca Neri, Jonathan Dukes, Daniel C Brennan, Paulo R Salvalaggio, Susmitha Seelam, Srividya Desiraju, Mark Schnitzler

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Clinical target achievement is associated with better quality of life among dialysis patients: results from a continuous quality improvement program in a Portuguese healthcare network.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luca NeriDipartimento di Medicina del Lavoro, Clinica del Lavoro L Devoto-Divisione di Ergonomia e Psicologia del Lavoro, Università degli Studi di Milano, Via San Barnaba 8, Milan, Italy. lneri@slu.edu
Jonathan Dukes
Daniel C Brennan
Paulo R Salvalaggio
Susmitha Seelam
Srividya Desiraju
Mark Schnitzler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe sought to determine the association between health-related quality of life (HRQOL) and graft function in renal transplant recipients. DESIGN AND

methodsWe enrolled 577 kidney transplant recipients aged 18-74 years (response rate 87%). Recipients with multiple or multi-organ transplantation, creatine kinase >200 U/L, acute renal failure or cellular rejection (n = 64), and without creatinine assessments in 3 months pre-enrollment (n = 127) were excluded. The questionnaire included Euro QOL 5 Dimensions (EQ-5D), Health Utility Index III (HUI-III), Kidney Disease Quality of Life-36 (KDQOL36) which include a generic section (RAND SF-12). Data on medical conditions, therapy regimens, and biochemistry results were extracted from clinical charts. We used general linear models adjusted for demographic, socioeconomic, and clinical characteristics to assess the association between HRQOL and severity of chronic kidney disease (CKD).

resultsPatients with more advanced CKD were more likely to be African-American, covered by public insurance, more likely to have shorter time after transplantation, higher phosphorus and lower hemoglobin, serum albumin, and calcium levels. All HRQOL scales were inversely associated with CKD severity. All associations were robust to adjustment for possible confounders.

conclusionsSeveral health-related quality of life dimensions may be affected by poor renal function after transplantation.

Indexed as

Kidney TransplantationQuality of LifeSickness Impact ProfileAcute Kidney InjuryAdolescentAdultAgedFemaleHost vs Graft ReactionHumansKidney Failure, ChronicLogistic ModelsMaleMedical RecordsMiddle AgedSelf Report

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.