Evidence map›Paper›PMID 21479777›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2011

Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L).

M Herdman, C Gudex, A Lloyd, Mf Janssen, P Kind, D Parkin, G Bonsel, X Badia

98 registry-linked trialsAbstract readValidation Study
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 98 registered trials, which are not on this map. Cited by 5,715 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5,715citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02374307 nacompletednot on this mapstarted 2016, after this paper: background citation

Effect of a Falls-prevention Exercise Program on Health-related Quality of Life in Older Fallers Receiving Home Care. A Randomized Controlled Trial

TypeinterventionalSponsorOslo Metropolitan UniversityRan2016 to 2017Enrolled155ConditionsAccidental FallsArmsExercise and education
NCT02591901 phase2completednot on this mapstarted 2018, after this paper: background citation

Prevention of Recurrent Symptomatic Urinary Tract Infections in Participants With Chronic Neurogenic Bladder Dysfunction: A Mixed Method Study

TypeinterventionalSponsorBuckinghamshire Healthcare NHS TrustRan2018 to 2019Enrolled48ConditionsUTI, Neurogenic Bladder, Antibiotic ResistanceArmsUro vaxom, Placebo comparator
NCT02693873 nacompletednot on this mapstarted 2016, after this paper: background citation

STOP OA: A PILOT STUDY - Adaptation and Evaluation of a Targeted, Evidence-based, Integrated Patient Education and Exercise Program to Prevent the Progression of Hip and Knee Osteoarthritis Symptoms

TypeinterventionalSponsorAileen DavisRan2016 to 2017Enrolled61ConditionsOsteoarthritisArmsGLA:D Canada (education and neuromuscular exercise program)
NCT02745236 nacompletednot on this mapstarted 2016, after this paper: background citation

The Effect of Nurse Practitioner-Led Care on Health Related Quality Of Life in Adult Patients With Atrial Fibrillation - A Randomized Trial

TypeinterventionalSponsorUniversity of AlbertaRan2016 to 2020Enrolled150ConditionsAtrial FibrillationArmsNurse Practitioner Led-Care, Cardiologist Led-Care
NCT02863211 unknown statusnot on this mapstarted 2015, after this paper: background citation

The Assessment of Large and Small Artery Elasticity for the Early Detection of Cardiovascular Disease

Typeobservational_patient_registrySponsorSt. Boniface HospitalRan2015 to 2022Enrolled1,000ConditionsCardiovascular Diseases, Vascular Stiffness
NCT03068286 naterminatednot on this mapstarted 2017, after this paper: background citation

Tailored Internet-delivered Cognitive Behavioural Therapy for Depression and Anxiety in Patients With a Long-term Condition (Chronic Pain, COPD and Diabetes).

TypeinterventionalSponsorDerek RichardsRan2017 to 2018Enrolled20ConditionsDiabetes, Chronic Pain, COPD, CHD - Coronary Heart DiseaseArmsSpace in Diabetes, Space in COPD, Space in Chronic Pain
NCT03072810 nacompletednot on this mapstarted 2017, after this paper: background citation

Does the Positive Mindfulness Program Increase Wellbeing in People With Chronic Pain?

TypeinterventionalSponsorCanterbury Christ Church UniversityRan2017 to 2018Enrolled73ConditionsPain, ChronicArmsPositive mindfulness program
NCT03136367 nacompletednot on this mapstarted 2017, after this paper: background citation

Comparative Effectiveness of Encounter Decision Aids for Early-Stage Breast Cancer Across Socioeconomic Strata

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2017 to 2019Enrolled571ConditionsBreast CancerArmsOption Grid, Picture Option Grid
NCT03248869 nacompletednot on this mapstarted 2015, after this paper: background citation

Asthma Mobile Health Application 2.0

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2015 to 2017Enrolled7,752ConditionsAsthmaArmsCurrent Daily Survey, Mobile Health App
NCT03250988 completednot on this mapstarted 2018, after this paper: background citation

Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility

TypeobservationalSponsorVanderbilt University Medical CenterRan2018 to 2018Enrolled60ConditionsSpasticity, Muscle, Muscular Diseases, Musculoskeletal Disease, Muscle HypertoniaArmsNeurological Examination
NCT03355677 nacompletednot on this mapstarted 2017, after this paper: background citation

A Clinical Interventional Study Into Airways Disease Case Finding and Complex Case Management

TypeinterventionalSponsorUniversity of SouthamptonRan2017 to 2019Enrolled327ConditionsCOPD, AsthmaArmsCase finding Clinic, At Risk Case Clinics, Usual Care
NCT03484351 nacompletednot on this mapstarted 2018, after this paper: background citation

Evaluating the Feasibility of Providing a Newly Developed Multifactorial Falls Prevention Programme for Community-dwelling Patients After Stroke.

TypeinterventionalSponsorCurtin UniversityRan2018 to 2018Enrolled5ConditionsStrokeArmsFall Monty Activity Programme (FallMAP)
NCT03484715 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Feasibility of a Physical Activity Programme Embedded Into the Daily Lives of Older Adults Living in Nursing Homes: a Randomised Controlled Pilot Feasibility Study

TypeinterventionalSponsorNational University of Ireland, Galway, IrelandRan2018 to 2019Enrolled40ConditionsOld AgeArmsPhysical Activity Intervention
NCT03551483 naunknown statusnot on this mapstarted 2018, after this paper: background citation

ArtontheBrain: An Inclusive Evidence-based Cognitive Health App for Older Adults to Promote Aging at Home

TypeinterventionalSponsorBaycrestRan2018 to 2019Enrolled110ConditionsCognitive Impairment, Mild Cognitive Impairment, Dementia, Age-related Cognitive DeclineArmsArtontheBrain, Seniors Online Victoria
NCT03604809 nacompletednot on this mapstarted 2019, after this paper: background citation

Guided Occupational Therapist Cognitive Interventions in Critically Ill Patients

TypeinterventionalSponsorAlberta Health Services, CalgaryRan2019 to 2020Enrolled70ConditionsDeliriumArmsOT Guided Cognitive Interventions
NCT03653234 nacompletednot on this mapstarted 2019, after this paper: background citation

TV-based Assistive Integrated Service to Support European Adults Living With Mild Dementia or Mild Cognitive Impariment

TypeinterventionalSponsorFundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludRan2019 to 2020Enrolled404ConditionsMild Cognitive Impairment, Mild DementiaArmsTV-based Assistive Integrated Service
NCT03763825 naunknown statusnot on this mapstarted 2019, after this paper: background citation

A Pilot Trial of the Mini-AFTERc Intervention to Manage Fear of Cancer Recurrence in Breast Cancer Patients

TypeinterventionalSponsorUniversity of St AndrewsRan2019 to 2020Enrolled133ConditionsBreast Cancer, Fear of CancerArmsMini-AFTERc
NCT03806114 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Impact of Dislocation Precautions on Fear and Function in Patients Undergoing Hip Replacement

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2019 to 2023Enrolled212ConditionsArthroplasty, Hip Replacement, Arthroplasties, Hip Replacement, Health-Related Quality Of LifeArmsPosterior Approach Precautions, Anterior Approach Precautions, No Precautions
NCT04144647 naunknown statusnot on this mapstarted 2019, after this paper: background citation

The Relationship Between Dual-task Gait Performance, Physical Activity Levels, Sleep and Aging in Healthy Adults

TypeinterventionalSponsorKing's College LondonRan2019 to 2020Enrolled100ConditionsHealthy, AdultsArmsSingle testing session
NCT04144686 naunknown statusnot on this mapstarted 2019, after this paper: background citation

'Effectiveness of Customised Vestibular Rehabilitation With and Without Additional Dual-Task Training in Persons With a Chronic Vestibular Disorder. A Randomised Controlled Trial'

TypeinterventionalSponsorKing's College LondonRan2019 to 2020Enrolled48ConditionsVestibularArmsPhysiotherapy Rehabilitation
NCT04148508 nacompletednot on this mapstarted 2020, after this paper: background citation

Assessing and Enhancing Emotional Competence for Well-Being in Young Adults: A Principled, Evidence-based, Mobile-health Approach to Prevent Mental Disorders and Promote Mental Well-being

TypeinterventionalSponsorUniversity of ExeterRan2020 to 2022Enrolled3,794ConditionsWellbeing, Mental DisorderArmsTailored Emotional Competence Self-help, Cognitive-behavioural Approach, Self-monitoring
NCT04230239 phase2completednot on this mapstarted 2019, after this paper: background citation

A Phase II, Multicentre, Open Label Clinical Trial to Assess the Efficacy and Toxicity of Induction and Consolidation With CPX-351 for Patients Aged 60 to 75 Years With Secondary or High-risk Acute Myeloid Leukemia

TypeinterventionalSponsorPETHEMA FoundationRan2019 to 2021Enrolled59ConditionsNewly Diagnosed Secondary or High Risk AMLArmsCPX-351
NCT04233970 nacompletednot on this mapstarted 2020, after this paper: background citation

Development and Evaluation of an Interactive Web-based Programme on Relapse Management for People With Multiple Sclerosis - a Randomized Controlled Trial With Mixed Methods Process Evaluation

TypeinterventionalSponsorUniversitätsklinikum Hamburg-EppendorfRan2020 to 2023Enrolled160ConditionsMultiple Sclerosis, Relapsing-RemittingArmsweb-based intervention programme, web-based information material offered via the same platform (broca®) in addition to usual care
NCT04249960 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.

TypeinterventionalSponsorUniversity of Geneva, SwitzerlandRan2019 to 2022Enrolled200ConditionsPsychiatric Disorder, TransitionArmsManaged transition
NCT04289077 completednot on this mapstarted 2020, after this paper: background citation

The Evaluation of Health-related Quality of Life Issues Experienced by Patients With Desmoid-type Fibromatosis

TypeobservationalSponsorErasmus Medical CenterRan2020 to 2021Enrolled156ConditionsDesmoid Tumor, Desmoid-type FibromatosisArmsQuestionnaires
NCT04300660 unknown statusnot on this mapstarted 2017, after this paper: background citation

POPARTS Study- Post-Operative Pain After Recovery in Thoracic Surgery: Evaluation of the Persistence of Painful Symptoms and the Incidence of Neuropathic Pain After Resective Lung Surgery

Typeobservational_patient_registrySponsorUniversity of TriesteRan2017 to 2020Enrolled250ConditionsNeuropathic Pain, Post Operative Pain, Thoracic SurgeryArmsneuropathic pain after thoracic surgery
NCT04313829 nacompletednot on this mapstarted 2017, after this paper: background citation

Impact of Pharmacist Counseling on the Health-related Quality of Life of Patients With Type 2 Diabetes Mellitus: a Cluster Randomized Controlled Study

TypeinterventionalSponsorUniversitas PadjadjaranRan2017 to 2018Enrolled220ConditionsType 2 Diabetes MellitusArmsPharmacist Counseling Intervention
NCT04409288 phase3terminatednot on this mapstarted 2020, after this paper: background citation

Patient Preference of Apalutamide Versus Enzalutamide in Patients With Recurrent or Metastatic Hormone-Sensitive Prostate Cancer: An Open-label, Randomized, Cross-Over Trial.

TypeinterventionalSponsorChinese University of Hong KongRan2020 to 2023Enrolled74ConditionsProstate CancerArmsApalutamide, Enzalutamide
NCT04498585 nasuspendednot on this mapstarted 2021, after this paper: background citation

Virtual Reality Stimulation to Relax and Reduce the Incidence of Delirium

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2021 to 2023Enrolled920ConditionsDelirium, Cognitive ImpairmentArmsVR Stimulation
NCT04613713 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effectiveness and Cost-utility of Somatocognitive Therapy Versus Treatment as Usual for Provoked (Localized) Vestibulodynia - a Randomized Clinical Trial (ProLoVe Study)

TypeinterventionalSponsorOslo Metropolitan UniversityRan2021 to 2025Enrolled128ConditionsVulvodynia, VestibulodyniaArmsSomatocognitive physiotherapy, Treatment as usual
NCT04623593 narecruitingnot on this mapstarted 2022, after this paper: background citation

Economic Evaluation of Anterior Cervical Discectomy With Arthroplasty Versus Anterior Cervical Discectomy With Fusion in the Surgical Treatment of Cervical Degenerative Disc Disease, a Randomized Controlled Trial

TypeinterventionalSponsorValérie SchuermansRan2022 to 2028Enrolled198ConditionsRadiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical RegionArmsACDF, ACDA
NCT04631471 phase3recruitingnot on this mapstarted 2021, after this paper: background citation

Regeneration in Cervical Degenerative Myelopathy - a Multi-centre, Double-blind, Randomised, Placebo Controlled Trial Assessing the Efficacy of Ibudilast as an Adjuvant Treatment to Decompressive Surgery for Degenerative Cervical Myelopathy

TypeinterventionalSponsorCambridge University Hospitals NHS Foundation TrustRan2021 to 2026Enrolled400ConditionsMyelopathy, Spinal Cord DiseasesArmsIbudilast, Cervical decompressive surgery, Matching placebo
NCT04663685 nacompletednot on this mapstarted 2020, after this paper: background citation

MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.

TypeinterventionalSponsorUniversity of WaterlooRan2020 to 2021Enrolled30ConditionsArthritis, Cancer, Cardiovascular Diseases, Chronic Lung DiseaseArmsExercise program, Nutrition education
NCT04687761 phase1 / phase2completednot on this mapstarted 2020, after this paper: background citation

A Phase I-II, Multicentre, Open Label Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine, Plus Venetoclax and Quizartinib in Newly Diagnosed Acute Myeloid Leukemia Patients Aged Equal or More Than 60 Years Old Ineligible for Standard Induction Chemotherapy

TypeinterventionalSponsorPETHEMA FoundationRan2020 to 2025Enrolled113ConditionsLeukemia, Myeloid, Acute, De Novo, Age More 60yrArmsAzacitidine, Venetoclax, Quizartinib, Cytarabine
NCT04706624 nacompletednot on this mapstarted 2021, after this paper: background citation

Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics

TypeinterventionalSponsorHanoi Medical UniversityRan2021 to 2025Enrolled667ConditionsMethamphetamine Abuse, Opioid-use Disorder, HIV SeropositivityArmsContingency management (12 weeks), Contingency management (6 weeks), SMS reminders, Matrix only, Matrix + Contingency management
NCT04741932 nacompletednot on this mapstarted 2021, after this paper: background citation

Interprofessional Dementia Care: Redistribution of Tasks Between Physicians and Qualified Nurses in Primary Care

TypeinterventionalSponsorGerman Center for Neurodegenerative Diseases (DZNE)Ran2021 to 2023Enrolled471ConditionsDementia, Nurse's Role, Nurse Physician RelationsArmsDementia Care Management (DCM)
NCT04803825 nacompletednot on this mapstarted 2021, after this paper: background citation

The Feasibility of Heavy-slow Resistance Training, Radial Extracorporeal Shockwave Therapy (rESWT) and Information and Advice. The NOrwegian Tennis Elbow (NOTE) Study

TypeinterventionalSponsorOslo University HospitalRan2021 to 2023Enrolled100ConditionsLateral Epicondylitis, Tennis Elbow, Tendinopathy, ElbowArmsHeavy Slow Exercises, Extracorporeal Shock wave therapy, Information and advice
NCT04886791 narecruitingnot on this mapstarted 2021, after this paper: background citation

Vaginal Hysterectomy Versus Vaginal Assisted NOTES Hysterectomy (VANH): a Randomised Controlled Trial

TypeinterventionalSponsorZuyderland Medisch CentrumRan2021 to 2025Enrolled124ConditionsHysterectomy, Natural Orifice Transluminal Endoscopic Surgery, Vaginal HysterectomyArmsVaginal NOTES hysterectomy, Vaginal hysterectomy
NCT04921176 completednot on this mapstarted 2020, after this paper: background citation

Evaluating Quality of Life of AF Patients Following a Bleed

Typeobservational_patient_registrySponsorSwansea UniversityRan2020 to 2022Enrolled32ConditionsAtrial Fibrillation
NCT04985552 nanot yet recruitingnot on this mapstarted 2021, after this paper: background citation

Closed Incision Negative Pressure Therapy Compared to Conventional Dressing Following Autologous Abdominal Tissue Breast Reconstruction: A Pilot Randomized Control Trial

TypeinterventionalSponsorMcMaster UniversityRan2021 to 2022Enrolled24ConditionsBreast CancerArmsDIEP Breast Reconstruction, ciNPT, Conventional Tape Dressings
NCT04995705 naterminatednot on this mapstarted 2019, after this paper: background citation

A Randomised Waiting List Controlled Study of Group Based Acceptance and Commitment Therapy (ACT) to Promote Psychological Wellbeing in People Living With the Consequences of Stroke or Acquired Brain Injury

TypeinterventionalSponsorAnna PenningtonRan2019 to 2020Enrolled39ConditionsStroke, Acquired Brain Injury, Acceptance and Commitment Therapy, Brain InjuriesArmsAcceptance and Commitment Therapy (ACT)
NCT05003180 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

SunBurst (StUdy oN Burst Fractures) - a National, Multicenter, Register-based, Randomized Controlled Trial on Thoracolumbar Burst Fractures

TypeinterventionalSponsorUppsala UniversityRan2021 to 2036Enrolled202ConditionsThoracolumbar Burst FractureArmsSurgical stabilization
NCT05033210 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Prevention of Mental Health Problems Among Persons Without Personal Housing in the Context of the COVID-19 Epidemic: a Randomized Controlled Trial

TypeinterventionalSponsorANRS, Emerging Infectious DiseasesRan2022 to 2023Enrolled210ConditionsPsychological Distress, Quality of Life, Psychosocial InterventionArmsPsychological First Aid (PFA), Care as Usual (CAU), Doing What Matters in Times of Stress (DWM), Problem Management Plus (PM+)
NCT05093426 completednot on this mapstarted 2022, after this paper: background citation

Personalised Electronic Record Supported Two-Stage Observational Study of Sleep in Patients With Breast Cancer

TypeobservationalSponsorClosed Loop MedicineRan2022 to 2022Enrolled226ConditionsInsomnia, Breast CancerArmsStage 2 Digital sleep diary app
NCT05115305 completednot on this mapstarted 2022, after this paper: background citation

Validation of a Level 2 Sleep Study Device

TypeobservationalSponsorCerebra MedicalRan2022 to 2022Enrolled84ConditionsSleep Apnea
NCT05199311 phase1 / phase2suspendednot on this mapstarted 2022, after this paper: background citation

A Phase I/II Study of Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Patients With Newly Diagnosed Transplant Eligible Multiple Myeloma

TypeinterventionalSponsorHackensack Meridian HealthRan2022 to 2027Enrolled66ConditionsMultiple MyelomaArmsCarfilzomib, Iberdomide, Oral Dexamethasone
NCT05212571 naenrolling by invitationnot on this mapstarted 2022, after this paper: background citation

Long-term Pain Modulation by Intravenous Esketamine in Complex Regional Pain Syndrome: a Non-inferiority Study

TypeinterventionalSponsorErasmus Medical CenterRan2022 to 2027Enrolled60ConditionsComplex Regional Pain Syndromes, CRPS (Complex Regional Pain Syndromes)ArmsS-ketamine infusion inpatient setting, S-ketamine infusion outpatient setting
NCT05256628 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Early Versus Delayed Weightbearing in FemoroAcetabular Impingement Syndrome Patients Undergoing Treatment With Arthroscopic HIP Osteochondroplasty: a Randomized Controlled Non-inferiority Trial

TypeinterventionalSponsorWomen's College HospitalRan2022 to 2024Enrolled240ConditionsFemoroacetabular Impingement SyndromeArmsEarly Weightbearing, Protected Weightbearing
NCT05302518 nacompletednot on this mapstarted 2022, after this paper: background citation

Virtual Reality for AnxIety Disorders - Randomized Controlled Trial

TypeinterventionalSponsorRegion of Southern DenmarkRan2022 to 2025Enrolled80ConditionsSocial Anxiety, Social PhobiaArmsCognitive behavioral therapy with exposure in virtual reality, Cognitive behavioral therapy with exposure in vivo
NCT05306548 phase4active not recruitingnot on this mapstarted 2022, after this paper: background citation

The NOR-CACTUS Trial - A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel Syndrome

TypeinterventionalSponsorDiakonhjemmet HospitalRan2022 to 2028Enrolled258ConditionsCarpal Tunnel SyndromeArmsSurgical carpal tunnel release, Injection, Triamcinolone Hexacetonide, Per 5 Mg
NCT05307120 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Lifestyle Monitoring and Coaching Using the Mobile DIAMETER Application in Secondary Care (DIAMETER-1, Phase 2 - Feasibility Study).

TypeinterventionalSponsorUniversity of TwenteRan2022 to 2024Enrolled80ConditionsDiabetes Mellitus, Type 2ArmsDiameter integrated in secondary diabetes care
NCT05368337 unknown statusnot on this mapstarted 2022, after this paper: background citation

Feasibility and Usability of Intrinsic Capacity Monitoring With Eforto and Its Predictive Value for Health Outcomes in Older Community-dwelling Persons

TypeobservationalSponsorVrije Universiteit BrusselRan2022 to 2023Enrolled160ConditionsFrailty
NCT05415592 withdrawnnot on this mapstarted 2023, after this paper: background citation

A Multi-Center, Post-Market, Single-Arm, Observational Clinical Follow-Up Study of Patients Undergoing Radial Head Replacement Using the DePuy Synthes Radial Head Replacement System for Partial Replacement of the Elbow Joint

TypeobservationalSponsorDePuy Synthes Products, Inc.Ran2023 to 2030Enrolled0ConditionsRadial Head FracturesArmsDePuy Synthes Radial Head Replacement System
NCT05591820 narecruitingnot on this mapstarted 2022, after this paper: background citation

A Randomized Controlled Trial on Brief Behavioral Parent Training Versus Care as Usual in Children With Behavioral Difficulties

TypeinterventionalSponsorAccareRan2022 to 2026Enrolled93ConditionsDisruptive Behavior, Behavior Problems, Behavioral Problems, Problem BehaviorsArmsBrief behavioral parent training with optional booster sessions, Care as usual
NCT05783414 nacompletednot on this mapstarted 2023, after this paper: background citation

Effectiveness and Cost-effectiveness of Virtually Delivered Cognitive Stimulation Therapy (vCST) and Online Dementia Carer Support

TypeinterventionalSponsorThe University of Hong KongRan2023 to 2024Enrolled156ConditionsDementiaArmsf2f CST, f2f carer support, vCST, online carer support
NCT05784428 narecruitingnot on this mapstarted 2025, after this paper: background citation

Single vs. Multiple Fraction Non-Inferiority Trial of Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligo-metastases/Progression: SIMPLIFY-SABR-COMET

TypeinterventionalSponsorRobert OlsonRan2025 to 2035Enrolled598ConditionsOligometastatic Disease, Oligoprogression, Toxicity Due to Radiotherapy, Quality of LifeArmsSingle fraction SABR, Multiple fraction SABR, QoL reporting alone, QoL reporting, symptom screen and healthcare provider intervention
NCT05846087 nacompletednot on this mapstarted 2023, after this paper: background citation

Mobile App-delivered Sleep Therapy (SleepFix) for Individuals With Chronic Low Back Pain and Insomnia: a Randomized Controlled Trial With Internal Pilot Study

TypeinterventionalSponsorWoolcock Institute of Medical ResearchRan2023 to 2025Enrolled106ConditionsChronic Low-back Pain, InsomniaArmssleep retraining therapy, sleep health education modules
NCT05907941 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Closed Incision Negative Pressure Therapy Compared to Conventional Dressing Following Autologous Abdominal Tissue Breast Reconstruction: A Randomized Control Trial

TypeinterventionalSponsorMcMaster UniversityRan2024 to 2026Enrolled114ConditionsBreast Cancer, Wound Dehiscence, SurgicalArmsciNPT, Conventional Tape Dressings, DIEP Breast Reconstruction
NCT05947903 unknown statusnot on this mapstarted 2024, after this paper: background citation

Validation of the European Oncology Quality of Life Toolkit. A European Pilot Survey.

TypeobservationalSponsorFondazione IRCCS Istituto Nazionale dei Tumori, MilanoRan2024 to 2024Enrolled4,000ConditionsCancer, Survivorship, Palliative CareArmsAdministration of the EUonQoL-Kit - Active Treatment questionnaire, Administration of the EUonQoL-Kit - Survivors questionnaire, Administration of the EUonQoL-Kit - Palliative Care questionnaire
NCT06016647 unknown statusnot on this mapstarted 2023, after this paper: background citation

Precision Multi-Axis Pain Assessment of Injured Workers to Improve Treatment and Work Outcomes

TypeobservationalSponsorDave WaltonRan2023 to 2025Enrolled350ConditionsMusculoskeletal Injury, Musculoskeletal Strain, Low Back Pain, Neck PainArmsMusculoskeletal-specific WSIB programs of care
NCT06018272 narecruitingnot on this mapstarted 2024, after this paper: background citation

Mentalisierungsbasierte Therapie Versus Bona-fide-Therapie für Patient:Innen Mit Borderline-Persönlichkeitsstörung in Deutschland (MaGnet): Eine Prospektive, Multizentrische Randomisiert-kontrollierte Studie Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany (MAGNET): a Prospective, Multi-centre Randomized Controlled Trial

TypeinterventionalSponsorHeidelberg UniversityRan2024 to 2028Enrolled304ConditionsBorderline Personality DisorderArmsMentalization-Based Treatment (MBT), Bona-Fide Treatment in Germany (BFT)
NCT06111820 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Evaluation of Training Curriculum and Service of Improving Access to Community Therapies

TypeinterventionalSponsorMind Mental Health Hong Kong LimitedRan2022 to 2024Enrolled330ConditionsDepression, Anxiety, Mental Health Issue, StressArmsImproving Access to Community Therapies (iACT)
NCT06195423 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Stop Osteoarthritis (SOAR) Hybrid Effectiveness-Implementation Type 1 Randomized Controlled Trial for Young People At-High-Risk of Early Onset Knee Osteoarthritis

TypeinterventionalSponsorUniversity of British ColumbiaRan2024 to 2028Enrolled210ConditionsKnee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, KneeArmsStop OsteoARthritis (SOAR) program, Living Well after ACLR program
NCT06252259 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Choose to Move (CTM): Implementation and Impact Evaluation of an Adapted Health-Promoting Program for Equity-Deserving Older Adults

TypeinterventionalSponsorUniversity of British ColumbiaRan2024 to 2027Enrolled336ConditionsAging, Mobility Limitation, Physical Inactivity, Sedentary BehaviorArmsChoose to Move
NCT06295250 narecruitingnot on this mapstarted 2024, after this paper: background citation

ASHA Bangladesh--An Integrated Intervention to Address Depression in Low Income Rural Women

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2024 to 2026Enrolled600ConditionsDepression, Economic Vulnerability, Anxiety, Culture Specific SymptomsArmsManualized Group Based Psychotherapy, Poverty Alleviation
NCT06324526 completednot on this mapstarted 2017, after this paper: background citation

What is the Effect of Bariatric Surgery on Health-related Quality of Life? Analysis of the United Kingdom National Bariatric Surgery Registry

TypeobservationalSponsorImperial College LondonRan2017 to 2022Enrolled2,160ConditionsQuality of Life, Obesity, Morbid, Bariatric Surgery Candidate
NCT06396702 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Emotion And Symptom-focused Engagement (EASE) Intervention for the Management of Emotional and Physical Symptoms Among Solid Organ Transplant Recipients-pilot Study

TypeinterventionalSponsorUniversity Health Network, TorontoRan2024 to 2027Enrolled120ConditionsTransplant, Failure,Kidney, Transplant, Failure, HeartArmsEASE-SOT
NCT06412341 nacompletednot on this mapstarted 2024, after this paper: background citation

A Feasibility Study to Inform an RCT to Evaluate 'Accepting Your Body After Cancer', an Online-delivered, Group-based CBT Body Image Intervention, for Women Who Have Received Treatment for Breast Cancer

TypeinterventionalSponsorUniversity of the West of EnglandRan2024 to 2025Enrolled120ConditionsBreast Cancer FemaleArmsAccepting your Body after Cancer, Macmillan body image booklet
NCT06459011 recruitingnot on this mapstarted 2024, after this paper: background citation

TAKINGCARE - TAcKlING the Needs of Carers of People With Chronic respirAtoRy disEases

TypeobservationalSponsorAveiro UniversityRan2024 to 2028Enrolled250ConditionsChronic Respiratory Disease
NCT06471452 naunknown statusnot on this mapstarted 2023, after this paper: background citation

To Live Better After Breast Cancer Treatment - a Randomized Pilot Trial of a Supportive and Person-centered Care Intervention in Primary Healthcare

TypeinterventionalSponsorKarolinska InstitutetRan2023 to 2025Enrolled40ConditionsBreast Cancer SurvivorshipArmsInteraktor
NCT06528132 narecruitingnot on this mapstarted 2024, after this paper: background citation

Social Worker-led Mindfulness-based Intervention for Managing Depressive Symptoms in Community-dwelling Older Adults in Hong Kong: A Randomised Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2024 to 2026Enrolled207ConditionsDepressive SymptomsArmsMindfulness-based intervention (MBI) (enhanced with peer supporters), Experimental: social worker-led MBI (without peer supporters)
NCT06559501 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Integrated Case Management for Improved Psychosocial and Physical Rehabilitation of Burn Survivors and Their Families Treated in Pakistan

TypeinterventionalSponsorPakistan Institute of Living and LearningRan2024 to 2026Enrolled1,045ConditionsUnintentional Burn Injury, Depression, Anxiety, BurnsArmsIntegrated case manager care
NCT06611319 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty

TypeinterventionalSponsorProf. Stavros Konstantinides, MDRan2024 to 2027Enrolled2,932ConditionsHip Arthroplasty, Total, Prevention of Venous ThromboembolismArmsPrevention of Venous Thromboembolism, Placebo Oral Tablet
NCT06648798 narecruitingnot on this mapstarted 2023, after this paper: background citation

LIMBER UniLeg: Rapid, On-demand, and Scaled-up Manufacturing of Customized Transtibial Prosthetic Legs for Amputees

TypeinterventionalSponsorLIMBER Prosthetics & Orthotics IncRan2023 to 2026Enrolled30ConditionsAmputation of Lower Limb, Prosthesis, Non-inferiority Trial of ProthesisArmsLimber Limb
NCT06726135 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

The National Rehabilitation Centre Dataset. Development of a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study

Typeobservational_patient_registrySponsorThomasCorbettRan2025 to 2025Enrolled50ConditionsPain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
NCT06782126 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Self-management Support After Burns: Study Protocol for a Multicenter Stepped-wedge Hybrid Type 2 Effectiveness-implementation Study

TypeobservationalSponsorMartini Hospital GroningenRan2024 to 2026Enrolled146ConditionsBurnsArmsBreeZe (Brandwonden en Zelfmanagement)
NCT06802406 narecruitingnot on this mapstarted 2025, after this paper: background citation

Nutrition OUtReach In Systems of Healthcare

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2029Enrolled210ConditionsALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Autologous Haemopoietic Stem Cell Transplant, CAR-T Cell Therapy, Food InsecurityArmsFood Bags
NCT06823739 nacompletednot on this mapstarted 2020, after this paper: background citation

Personalized Diet with or Without Physical Exercise Improves Nutritional Status, Muscle Strength, Physical Performance and Quality of Life in Malnourished Older Adult Patients: a Prospec-tive Randomized Controlled Study

TypeinterventionalSponsorIstanbul UniversityRan2020 to 2020Enrolled20ConditionsMalnourished Elderly, Quality of Life (QOL), BMI, Hand Grip StrengthArmsExercise
NCT06867081 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of a Customized Digital Platform to Increase Coordination of Care and Uptake of Evidence-based Practices: a Protocol for a Stepped-wedge Cluster Randomized Trial in Quebec

TypeinterventionalSponsorCentre for Interdisciplinary Research in Rehabilitation of Greater MontrealRan2025 to 2029Enrolled962ConditionsAquired Brain Injury, Traumatic Brain Injuries, Stroke, Cardiovascular DiseasesArmsThe intervention will be the BRILLIANT Platform, an online platform which provides five Modules aimed at increasing coordination of care and direct rehabilitation time
NCT06904872 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

A Phase 2, Placebo-Controlled, Randomized, Double-Blind Study of 2 Doses of Crofelemer for the Treatment of Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)

TypeinterventionalSponsorNapo Therapeutics, S.p.A.Ran2025 to 2027Enrolled18ConditionsShort Bowel Syndrome, Malabsorption Syndromes, Short Gut Syndrome, Post-Op ComplicationArmsCrofelemer Powder for Oral Solution, Matched Placebo Powder for Oral Solution
NCT06909240 narecruitingnot on this mapstarted 2025, after this paper: background citation

Progressive Gait Training After First-time Deep Venous Thrombosis: Clinical Effectiveness and Involved Mecanisms (The DVT-Cph RCT)

TypeinterventionalSponsorHvidovre University HospitalRan2025 to 2030Enrolled152ConditionsDeep Vein Thrombosis (DVT)ArmsProgressive gait training, Standard Care (in control arm)
NCT06953648 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplantation (REMM-HIIT-HCT)

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2030Enrolled126ConditionsHematopoietic Stem Cell Transplantation, Cardiorespiratory FitnessArmsHigh Intensity Interval Training
NCT06982716 narecruitingnot on this mapstarted 2025, after this paper: background citation

Evaluating the Clinical Effectiveness of a Community-based Hearing Aid Fitting Service Delivery Model Facilitated by Community Healthcare Workers (CHWs) Providing Smartphone-based In-situ and Pre-set Hearing Aid Fittings in Low- and Middle-income Communities (LMICs)

TypeinterventionalSponsorUniversity of PretoriaRan2025 to 2026Enrolled90ConditionsHearing LossArmsLexie Lumen Hearing Aids, Go Ultra Hearing Aids
NCT07000227 narecruitingnot on this mapstarted 2025, after this paper: background citation

Mechanism of FODMAP Restriction on Gut Microbiota and Gut Barrier Function in Functional Gastrointestinal Disorder Patients : A Randomised Controlled Trial

TypeinterventionalSponsorUniversiti Kebangsaan Malaysia Medical CentreRan2025 to 2026Enrolled60ConditionsFunctional Gastrointestinal Disorders (FGIDs), Irritable Bowel Syndrome (IBS), Functional DyspepsiaArmsLow FODMAP diet, Gentle FODMAP diet, Traditional Dietary Advice
NCT07021144 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

VA|PREVENTION: Randomized Controlled Trial of a Person-Centred Digital Intervention to Prevent Diabetes in High-Risk Adults

TypeinterventionalSponsorEgas Moniz - Cooperativa de Ensino Superior, CRLRan2025 to 2026Enrolled180ConditionsPre-diabetes, Pre-diabetic StateArmsVA, PREVENTION web application (digital intervention), Type 2 Diabetes Guidebook
NCT07073144 nacompletednot on this mapstarted 2025, after this paper: background citation

The Impact of 'Digital Strolling' on Depression and Quality of Life of People With Severe Mobility Impairment

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2025 to 2025Enrolled24ConditionsSevere Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete), PoliomyelitisArmsVirtual walking, Passive observing walking
NCT07172451 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy and Safety of Balanced Gelatin Solution for Fluid Infusion in Sepsis Patients Undergoing Emergency Abdominal Surgery: A Multicenter, Adaptive Designed, Randomized Controlled Trial

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2026 to 2028Enrolled318ConditionsSepsis, Intra-Abdominal InfectionsArmsBalanced Gelatin Solution, Acetate Ringer's Solution
NCT07349264 nacompletednot on this mapstarted 2025, after this paper: background citation

Boswellia Serrata, Curcumin, and Methylsulfonylmethane Combination Supplementation Improves Joint Health

TypeinterventionalSponsorNXTVSION SDN. BHD.Ran2025 to 2025Enrolled100ConditionsJoint, Joint DiseasesArmsFlexy3 Supplement (OriactivTM, Flexy3, Malaysia), Placebo
NCT07361640 narecruitingnot on this mapstarted 2026, after this paper: background citation

DiaMester: E-health Lifestyle Program for Improved Self-management and Remission of Type 2 Diabetes - a Pilot RCT

TypeinterventionalSponsorOslo University HospitalRan2026 to 2027Enrolled99ConditionsDiabetes Mellitus, Type 2Armse-health lifestyle program, Low calorie diet
NCT07552961 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating the Feasibility of a Comprehensive Prehabilitation Program for Use in Benign Prostatic Hyperplasia Patients Undergoing Holmium Laser Enucleation of the Prostate

TypeinterventionalSponsorUniversity of CalgaryRan2026 to 2027Enrolled40ConditionsBenign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Outflow ObstructionArmsComprehensive Prehabilitation Programming
NCT07579897 narecruitingnot on this mapstarted 2026, after this paper: background citation

Generalized Anxiety Disorder: A Randomized Non-inferiority Trial Comparing Group Metacognitive Therapy With Individual Metacognitive Therapy

TypeinterventionalSponsorSorlandet Hospital HFRan2026 to 2028Enrolled64ConditionsGeneralized Anxiety DisorderArmsIndividual Metacognitive Therapy, Group Metacognitive Therapy
NCT07580092 completednot on this mapstarted 2023, after this paper: background citation

Construct Validity and Responsiveness of EQ-5D-3L and EQ-5D-5L in Patients With Inflammatory Joint Disease

TypeobservationalSponsorKarolinska InstitutetRan2023 to 2026Enrolled6,967ConditionsAnkylosing Spondylitis, Rheumatoid Arthritis (RA), Psoriatic Arthritis, PolyarthritisArmsEQ-5D-5L
NCT07589127 narecruitingnot on this mapstarted 2026, after this paper: background citation

GENicular Nerve Block in KNEE Arthroplasty - The GENKNEE Trial

TypeinterventionalSponsorHelse Møre og Romsdal HFRan2026 to 2029Enrolled70ConditionsOsteoarthritis (OA) of the Knee, Total Knee Arthroplasty, Genicular Nerve BlockArmsPreoperative genicular nerve block (GNB), Placebo nerve block
NCT07590141 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

PRehabilitation In Advance of Major Elective Surgery: A Pilot Randomized Controlled Trial (PRIME Pilot)

TypeinterventionalSponsorQueen's UniversityRan2026 to 2028Enrolled120ConditionsPrehabilitation, Preoperative Care, Elective Surgical Procedures, Postoperative ComplicationsArmsVirtually Monitored Home-Based Prehabilitation Program
NCT07605754 recruitingnot on this mapstarted 2025, after this paper: background citation

Results of Nerve Surgery to Treat PostAmputation Pain (TreatPAP): a Prospective Study

TypeobservationalSponsorLeiden University Medical CenterRan2025 to 2029Enrolled98ConditionsAmputation NeuromaArmsFascicular split, Targeted Muscle Reinnervation
NCT07617155 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of GLP-1 Agonists on Prevention of HTG-Induced Acute Pancreatitis Recurrence: Protocol for a Randomized Clinical Trial

TypeinterventionalSponsorPeking Union Medical College HospitalRan2026 to 2028Enrolled396ConditionsHypertriglyceridemia Induced Acute Pancreatitis, Recurrent Acute Pancreatitis, Pancreatitis Relapsing, HypertriglyceridemiaArmsSemaglutide, Placebo (Normal Saline)
NCT07639957 recruitingnot on this mapstarted 2026, after this paper: background citation

What Role Does Gender Play in Relationship and Self Experiences of Individuals With Borderline Personality Disorder?

TypeobservationalSponsorUniversity Hospital HeidelbergRan2026 to 2027Enrolled15ConditionsBorderline Personality Disorder (BPD)
NCT07661472 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The FINGER Model for Preventing Cognitive Decline and Promoting Health - Older Peoples' Perspectives on Participating in the Projects "Hjärngänget" and "Hjärncellskapet" - a Pathway to Better Health.

TypeinterventionalSponsorUniversity of GavleRan2026 to 2028Enrolled180ConditionsOlder PeopleArmsFINGER model
3 · Its place in the literature

Who cites it

5,715 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Non-surgical treatment for lower limb apophyseal injuries.The Cochrane database of systematic reviews · 2026
    Pooled it
  6. Pooled it
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  11. Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Trial
  12. Patients with MASH experience worse health-related quality of life: a multinational real-world study using LiverMultiScan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Trial
  13. Trial
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  15. Cost-Effectiveness of Remote Cognitive-Behavioral-Based Therapy for Chronic Pain Among People With High-Impact Chronic Pain.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2026
    Trial
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5,655 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

M HerdmanInsight Consulting and Research, 08301 Mataró, Spain. michael.herdman@insightcr.com
C Gudex
A Lloyd
Mf Janssen
P Kind
D Parkin
G Bonsel
X Badia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis article introduces the new 5-level EQ-5D (EQ-5D-5L) health status measure.

methodsEQ-5D currently measures health using three levels of severity in five dimensions. A EuroQol Group task force was established to find ways of improving the instrument's sensitivity and reducing ceiling effects by increasing the number of severity levels. The study was performed in the United Kingdom and Spain. Severity labels for 5 levels in each dimension were identified using response scaling. Focus groups were used to investigate the face and content validity of the new versions, including hypothetical health states generated from those versions.

resultsSelecting labels at approximately the 25th, 50th, and 75th centiles produced two alternative 5-level versions. Focus group work showed a slight preference for the wording 'slight-moderate-severe' problems, with anchors of 'no problems' and 'unable to do' in the EQ-5D functional dimensions. Similar wording was used in the Pain/Discomfort and Anxiety/Depression dimensions. Hypothetical health states were well understood though participants stressed the need for the internal coherence of health states.

conclusionsA 5-level version of the EQ-5D has been developed by the EuroQol Group. Further testing is required to determine whether the new version improves sensitivity and reduces ceiling effects.

Indexed as

Health Status IndicatorsQuality of LifeActivities of Daily LivingAdultFemaleFocus GroupsHumansInterviews as TopicMaleMiddle AgedMobility LimitationPain MeasurementPsychometricsReproducibility of ResultsSelf CareSpain

Identifiers

PMID21479777
PMCPMC3220807

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.