ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2011
mec-associated dru typing in the epidemiological analysis of ST239 MRSA in Malaysia.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Genetic Diversity among Methicillin-ResistantTropical medicine and infectious disease · 2022Review
- Genotypic Characteristics and Correlation of Epidemiology ofAntibiotics (Basel, Switzerland) · 2020Article
- High prevalence of direct repeat unit types of 10di, 8 h and 8i among methicillin resistantAntimicrobial resistance and infection control · 2019Article
- Antibiotic Susceptibility, Virulence Pattern, and Typing ofFrontiers in microbiology · 2019Article
- Molecular and phenotypic characterization of methicillin-resistant Staphylococcus aureus isolates from a tertiary hospital in the Philippines.Tropical medicine and health · 2016Article
- Associations between dru Types and SCCmec cassettes.PloS one · 2013Article
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8 authors.
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Abstract
The usefulness of mec-associated dru typing in the epidemiological analysis of methicillin-resistant Staphylococcus aureus (MRSA) isolated in Malaysia was investigated and compared with pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and spa and SCCmec typing. The isolates studied included all MRSA types in Malaysia. Multilocus sequence type ST188 and ST1 isolates were highly clonal by all typing methods. However, the dru typing of ST239 isolates produced the clearest discrimination between SCCmec IIIa and III isolates, yielding more subtypes than any other method. Evaluation of the discriminatory power for each method identified dru typing and PFGE as the most discriminatory, with Simpson's index of diversity (SID) values over 89%, including an isolate which was non-typeable by spa, but dru-typed as dt13j. The discriminatory ability of dru typing, especially with closely related MRSA ST239 strains (e.g., Brazilian and Hungarian), underscores its utility as a tool for the epidemiological investigation of MRSA.
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