ArticleOptics letters2011
Compensation-free, all-fiber-optic, two-photon endomicroscopy at 1.55 μm.
Article in Optics letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Two-Photon Endomicroscopy for Image-Guided Magnetic Micro-Agents.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Video-rate two-photon microendoscopy using second harmonic resonance fiber scanning.Biomedical optics express · 2024Article
- Two-Photon Endoscopy: State of the Art and Perspectives.Molecular imaging and biology · 2023Review
- Label-free highly multimodal nonlinear endoscope.Optics express · 2022Article
- Double-Clad Fiber-Based Multifunctional Biosensors and Multimodal Bioimaging Systems: Technology and Applications.Biosensors · 2022Review
- Lissajous Scanning Two-photon Endomicroscope for In vivo Tissue Imaging.Scientific reports · 2019Article
- Fiber bundle shifting endomicroscopy for high-resolution imaging.Biomedical optics express · 2018Article
- Non-destructive two-photon excited fluorescence imaging identifies early nodules in calcific aortic-valve disease.Nature biomedical engineering · 2017Article
- Multi-photon vertical cross-sectional imaging with a dynamically-balanced thin-film PZT z-axis microactuator.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2017Article
- Fitting-free algorithm for efficient quantification of collagen fiber alignment in SHG imaging applications.Biomedical optics express · 2017Article
- Multiphoton microscopy for label-free identification of intramural metastasis in human esophageal squamous cell carcinoma.Biomedical optics express · 2017Article
- Dual-modality endomicroscopy with co-registered fluorescence and phase contrast.Biomedical optics express · 2016Article
- Miniature fiber-optic multiphoton microscopy system using frequency-doubled femtosecond Er-doped fiber laser.Biomedical optics express · 2016Article
- Noninvasive assessment of mitochondrial organization in three-dimensional tissues reveals changes associated with cancer development.International journal of cancer · 2015Article
- A high-efficiency fiber-based imaging system for co-registered autofluorescence and optical coherence tomography.Biomedical optics express · 2014Article
- Thermomechanical Actuator-Based Three-Axis Optical Scanner for High-Speed Two-Photon Endomicroscope Imaging.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2014Article
- Synthesis of dye conjugates to visualize the cancer cells using fluorescence microscopy.Applied optics · 2014Article
- Recent advances in hydrogen peroxide imaging for biological applications.Cell & bioscience · 2014Review
- All-near-infrared multiphoton microscopy interrogates intact tissues at deeper imaging depths than conventional single- and two-photon near-infrared excitation microscopes.Journal of biomedical optics · 2013Article
- Label-free multi-photon imaging using a compact femtosecond fiber laser mode-locked by carbon nanotube saturable absorber.Biomedical optics express · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We present an all-fiber-optic scanning multiphoton endomicroscope with 1.55 μm excitation without the need for prechirping femtosecond pulses before the endomicroscope. The system consists of a 1.55 μm femtosecond fiber laser, a customized double-clad fiber for light delivery and fluorescence collection, and a piezoelectric scan head. We demonstrate two-photon imaging of cultured cells and mouse tissue, both labeled with indocyanine green. Free-space multiphoton imaging with near-IR emission has previously shown benefits in reduced background fluorescence and lower attenuation for the fluorescence emission. For fiber-optic multiphoton imaging there is the additional advantage of using the soliton effect at the telecommunication wavelengths (1.3-1.6 μm) in fibers, permitting dispersion-compensation-free, small-footprint systems. We expect these advantages will help transition multiphoton endomicroscopy to the clinic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.