ArticleNature methods2011
A parallel microfluidic flow cytometer for high-content screening.
Article in Nature methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 102 citations in OpenAlex.
- Essential Fluidics for a Flow Cytometer.Current protocols · 2024Article
- Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities.Lab on a chip · 2022Review
- A review of microscopic cell imaging and neural network recognition for synergistic cyanobacteria identification and enumeration.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2022Review
- Advances in Microfluidics for the Implementation of Liquid Biopsy in Clinical Routine.Advances in experimental medicine and biology · 2022Article
- On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms.Sensors (Basel, Switzerland) · 2021Article
- Extremely High-Throughput Parallel Microfluidic Vortex-Actuated Cell Sorting.Micromachines · 2021Article
- Advances of Single-Cell Protein Analysis.Cells · 2020Review
- Spontaneous oscillations and negative-conductance transitions in microfluidic networks.Science advances · 2020Article
- Electro-actuated valves and self-vented channels enable programmable flow control and monitoring in capillary-driven microfluidics.Science advances · 2020Article
- Detection of Rare Objects by Flow Cytometry: Imaging, Cell Sorting, and Deep Learning Approaches.International journal of molecular sciences · 2020Review
- Graphene Optical Biosensors.International journal of molecular sciences · 2019Review
- Dynamic Measurement of Nanoflows: Analysis and Theory of an Optofluidic Flowmeter.Physical review applied · 2019Article
- Cell Cytometry: Review and Perspective on Biotechnological Advances.Frontiers in bioengineering and biotechnology · 2019Review
- Microfluidic Based Optical Microscopes on Chip.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018Review
- Bioengineered Liver Models for Drug Testing and Cell Differentiation Studies.Cellular and molecular gastroenterology and hepatology · 2018Review
- Microfluidic flow cytometry: The role of microfabrication methodologies, performance and functional specification.Technology · 2018Article
- Line-Focused Optical Excitation of Parallel Acoustic Focused Sample Streams for High Volumetric and Analytical Rate Flow Cytometry.Analytical chemistry · 2017Article
- Multiplex Immunoassays Utilizing Differential Affinity Using Aptamers Generated by MARAS.Scientific reports · 2017Article
- Microchip-based single-cell functional proteomics for biomedical applications.Lab on a chip · 2017Review
- Review: imaging technologies for flow cytometry.Lab on a chip · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A parallel microfluidic cytometer (PMC) uses a high-speed scanning photomultiplier-based detector to combine low-pixel-count, one-dimensional imaging with flow cytometry. The 384 parallel flow channels of the PMC decouple count rate from signal-to-noise ratio. Using six-pixel one-dimensional images, we investigated protein localization in a yeast model for human protein misfolding diseases and demonstrated the feasibility of a nuclear-translocation assay in Chinese hamster ovary (CHO) cells expressing an NFκB-EGFP reporter.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.