Evidence map›Paper›PMID 21477653›Full record

ReviewPharmacological research2011

Tea and cardiovascular disease.

Apranta Deka, Joseph A Vita

Abstract readReview
In one paragraph

Review in Pharmacological research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 181 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Green and black tea for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2013
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Plants Used as Antihypertensive.Natural products and bioprospecting · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Apranta DekaEvans Department of Medicine and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA 02118, United States.
Joseph A Vita
Boston University · US

Funding

Redox regulation in Endothelial Progenitor CellsP01HL081587 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALSH, KENNETH · 2005 to 2015
$21.5M
Vascular Consequences of Insulin Resistance and ObesityP50HL083801 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI VITA, JOSEPH A. · 2006 to 2010
$11.2M
Clinical Utility of Endothelial Function in PADR01HL075795 · NHLBI · BOSTON MEDICAL CENTER · PI VITA, JOSEPH A. · 2003 to 2007
$4.9M
Boston University Medical Center Leadership Program in Vascular MedicineK12HL083781 · NHLBI · BOSTON MEDICAL CENTER · PI EBERHARDT, ROBERT THOMAS · 2007 to 2013
$3.4M
Endothelial Insulin Resistance, Inflammation and Vascular Function in DiabetesR01HL102299 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM · 2010 to 2014
$2.0M
Determinants of Shear Stress-Mediated Arterial RemodelingR01HL083269 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI VITA, JOSEPH A. · 2006 to 2009
$1.9M
NHLBI NIH HHS HL081587NHLBI NIH HHS HL083269NHLBI NIH HHS HL083801NHLBI NIH HHS HL102299NHLBI NIH HHS HL75795NHLBI NIH HHS K12 HL083781NHLBI NIH HHS P01 HL081587NHLBI NIH HHS P50 HL083801NHLBI NIH HHS R01 HL075795NHLBI NIH HHS R01 HL083269NHLBI NIH HHS R01 HL102299
6 · The paper itself

Abstract

There is increasing evidence for a protective effect of tea consumption against cardiovascular disease. This review summarizes the available epidemiological data providing evidence for and against such an effect. We also review observational and intervention studies that investigated an effect of tea and tea extracts on cardiovascular risk factors, including blood pressure, serum lipids, diabetes mellitus, and obesity. Finally, we review potential mechanisms of benefit, including anti-inflammatory, anti-oxidant, and anti-proliferative effects, as well as favorable effects on endothelial function. Overall, the observational data suggest a benefit, but results are mixed and likely confounded by lifestyle and background dietary factors. The weight of evidence indicates favorable effects on risk factors and a number of plausible mechanisms have been elucidated in experimental and translational human studies. Despite the growing body evidence, it remains uncertain whether tea consumption should be recommended to the general population or to patients as a strategy to reduce cardiovascular risk.

Indexed as

TeaAnimalsCardiovascular DiseasesHumansRisk FactorsTea

Identifiers

PMID21477653
PMCPMC3123419
OpenAlexW1966599364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.