ArticlePreventing chronic disease2011
Identifying metabolic syndrome in African American children using fasting HOMA-IR in place of glucose.
Article in Preventing chronic disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01039116 (Taking Action Together), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Taking Action Together: Development, Implementation and Evaluation of Community-Based Programs That Aims to Reduce Risk of Type 2 Diabetes in High BMI African American Children.
Who cites it
14 citing papers in PubMed.
- An after-school dance and lifestyle education program reduces risk factors for heart disease and diabetes in elementary school children.Journal of pediatric endocrinology & metabolism : JPEM · 2012Trial
- Association between modified triglyceride glucose indices and stroke risk in middle-aged and older Chinese adults: a prospective cohort study.Cardiovascular diabetology · 2025Article
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study.Pediatrics · 2022Article
- A Novel Approach of Determining the Risks for the Development of Hyperinsulinemia in the Children and Adolescent Population Using Radial Basis Function and Support Vector Machine Learning Algorithm.Healthcare (Basel, Switzerland) · 2022Article
- Risk Assessment and Determination of Factors That Cause the Development of Hyperinsulinemia in School-Age Adolescents.Medicina (Kaunas, Lithuania) · 2021Article
- Serum Irisin Levels, Endothelial Dysfunction, and Inflammation in Pediatric Patients with Type 2 Diabetes Mellitus and Metabolic Syndrome.Journal of diabetes research · 2020Article
- Adolescent Obesity: Diet Quality, Psychosocial Health, and Cardiometabolic Risk Factors.Nutrients · 2019Review
- Pregnancy-Associated Hypertension and Offspring Cardiometabolic Health.Obstetrics and gynecology · 2018Observational
- Cardiometabolic Risk Variables in Preadolescent Children: A Factor Analysis.Journal of the American Heart Association · 2017Observational
- Cardiovascular Health Promotion in Children: Challenges and Opportunities for 2020 and Beyond: A Scientific Statement From the American Heart Association.Circulation · 2016Article
- Adipokines Vaspin and Visfatin in Obese Children.Open access Macedonian journal of medical sciences · 2015Article
- Prevalence of cardiometabolic risk factors and metabolic syndrome in obese Kuwaiti adolescents.Diabetes, metabolic syndrome and obesity : targets and therapy · 2014Article
- Obesity, metabolic syndrome, and insulin resistance in urban high school students of minority race/ethnicity.Archives of pediatrics & adolescent medicine · 2012Article
- Obesity and metabolic syndrome and functional and structural brain impairments in adolescence.Pediatrics · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMetabolic syndrome (MetS) is increasing among young people. We compared the use of homeostasis model assessment of insulin resistance (HOMA-IR) with the use of fasting blood glucose to identify MetS in African American children.
methodsWe performed a cross-sectional analysis of data from a sample of 105 children (45 boys, 60 girls) aged 9 to 13 years with body mass indexes at or above the 85th percentile for age and sex. Waist circumference, blood pressure, and fasting levels of blood glucose, insulin, triglycerides, and high-density lipoprotein cholesterol were measured.
resultsWe found that HOMA-IR is a stronger indicator of MetS in children than blood glucose. Using HOMA-IR as 1 of the 5 components, we found a 38% prevalence of MetS in this sample of African American children and the proportion of false negatives decreased from 94% with blood glucose alone to 13% with HOMA-IR. The prevalence of MetS was higher in obese than overweight children and higher among girls than boys.
conclusionUsing HOMA-IR was preferred to fasting blood glucose because insulin resistance was more significantly interrelated with the other 4 MetS components.
Indexed as
Identifiers
21477504PMC3103569What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.