ArticleGenome biology2011
An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations.
Article in Genome biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed.
- Genetic mapping of determinants in drug resistance, virulence, disease susceptibility, and interaction of host-rodent malaria parasites.Parasitology international · 2022Review
- Intra-host dynamics of co-infecting parasite genotypes in asymptomatic malaria patients.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018Article
- Malaria Genomics in the Era of Eradication.Cold Spring Harbor perspectives in medicine · 2017Review
- Microbial genome-wide association studies: lessons from human GWAS.Nature reviews. Genetics · 2017Review
- Population Structure Shapes Copy Number Variation in Malaria Parasites.Molecular biology and evolution · 2016Article
- Advances in genetics and genomics: use and limitations in achieving malaria elimination goals.Pathogens and global health · 2015Review
- A microarray platform and novel SNP calling algorithm to evaluate Plasmodium falciparum field samples of low DNA quantity.BMC genomics · 2014Article
- Exploring systems affected by the heat shock response in Plasmodium falciparum via protein association networks.International journal of computational biology and drug design · 2014Article
- Using genetic methods to define the targets of compounds with antimalarial activity.Journal of medicinal chemistry · 2013Review
- Long term persistence of clonal malaria parasite Plasmodium falciparum lineages in the Colombian Pacific region.BMC genetics · 2013Article
- Comparative Genomics and Systems Biology of Malaria ParasitesCurrent bioinformatics · 2012Article
- Article
- A major genome region underlying artemisinin resistance in malaria.Science (New York, N.Y.) · 2012Article
- Module-based subnetwork alignments reveal novel transcriptional regulators in malaria parasite Plasmodium falciparum.BMC systems biology · 2012Article
- DNA nanotechnology for nucleic acid analysis: DX motif-based sensor.Chembiochem : a European journal of chemical biology · 2011Article
- Genome-wide polymorphisms and development of a microarray platform to detect genetic variations in Plasmodium yoelii.Molecular and biochemical parasitologyArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
We present an optimized probe design for copy number variation (CNV) and SNP genotyping in the Plasmodium falciparum genome. We demonstrate that variable length and isothermal probes are superior to static length probes. We show that sample preparation and hybridization conditions mitigate the effects of host DNA contamination in field samples. The microarray and workflow presented can be used to identify CNVs and SNPs with 95% accuracy in a single hybridization, in field samples containing up to 92% human DNA contamination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.