Evidence map›Paper›PMID 21477180›Full record

ArticleTraffic (Copenhagen, Denmark)2011

Quantitative proteomics of yeast post-Golgi vesicles reveals a discriminating role for Sro7p in protein secretion.

Annabelle Forsmark, Guendalina Rossi, Ingrid Wadskog, Patrick Brennwald, Jonas Warringer, Lennart Adler

Open access · bronzeAbstract read
In one paragraph

Article in Traffic (Copenhagen, Denmark), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Annabelle ForsmarkDepartment of Cell and Molecular Biology, Microbiology, University of Gothenburg, Box 462, SE-405 30 Gothenburg, Sweden.
Guendalina Rossi
Ingrid Wadskog
Patrick Brennwald
Jonas Warringer
Lennart Adler
University of Gothenburg · SEUniversity of North Carolina at Chapel Hill · USJönköping University · SE

Funding

REGULATION OF EXOCYTOSIS BY A RHO GTPPASER01GM054712 · NIGMS · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI PATRICK J BRENNWALD · 1998 to 2026
$9.5M
NIGMS NIH HHS R01 GM054712
6 · The paper itself

Abstract

We here report the first comparative proteomics of purified yeast post-Golgi vesicles (PGVs). Vesicle samples isolated from PGV-accumulating sec6-4 mutants were treated with isobaric tags (iTRAQ) for subsequent quantitative tandem mass spectrometric analysis of protein content. After background subtraction, a total of 66 vesicle-associated proteins were identified, including known or assumed vesicle residents as well as a fraction not previously known to be PGV associated. Vesicles isolated from cells lacking the polarity protein Sro7p contained essentially the same catalogue of proteins but showed a reduced content of a subset of cargo proteins, in agreement with a previously shown selective role for Sro7p in cargo sorting.

Indexed as

Adaptor Proteins, Signal TransducingBiomarkersCytoplasmic VesiclesGolgi ApparatusProtein TransportProteomicsRecombinant Fusion ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdaptor Proteins, Signal TransducingBiomarkersRecombinant Fusion ProteinsSaccharomyces cerevisiae ProteinsSRO7 protein, S cerevisiae

Identifiers

PMID21477180
PMCPMC3926324
OpenAlexW2063119567

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.