Evidence map›Paper›PMID 21476929›Full record

ReviewCritical reviews in biochemistry and molecular biology2011

Molecular motors: directing traffic during RNA localization.

James A Gagnon, Kimberly L Mowry

Abstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Regulation and outcomes of localized RNA translation.Wiley interdisciplinary reviews. RNA · 2022
    Review
  7. Review
  8. Article
  9. PCID2, a subunit of theRNA biology · 2021
    Article
  10. Article
  11. Review
  12. Emerging Roles for 3' UTRs in Neurons.International journal of molecular sciences · 2020
    Review
  13. Article
  14. Article
  15. Organizing the oocyte: RNA localization meets phase separation.Current topics in developmental biology · 2020
    Article
  16. Review
  17. Review
  18. Review
  19. RNP transport in cell biology: the long and winding road.Current opinion in cell biology · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James A GagnonDepartment of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA.
Kimberly L Mowry

Funding

TRAINING IN MOLECULAR &CELL BIOLOGY &BIOCHEMISTRYT32GM007601 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 1985 to 2019
$6.4M
RNA Localization in Xenopus OocytesR01GM071049 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 2005 to 2018
$4.2M
NIGMS NIH HHS GM071049NIGMS NIH HHS R01 GM071049NIGMS NIH HHS T32 GM007601NIGMS NIH HHS T32-GM07601
6 · The paper itself

Abstract

RNA localization, the enrichment of RNA in a specific subcellular region, is a mechanism for the establishment and maintenance of cellular polarity in a variety of systems. Ultimately, this results in a universal method for spatially restricting gene expression. Although the consequences of RNA localization are well-appreciated, many of the mechanisms that are responsible for carrying out polarized transport remain elusive. Several recent studies have illuminated the roles that molecular motor proteins play in the process of RNA localization. These studies have revealed complex mechanisms in which the coordinated action of one or more motor proteins can act at different points in the localization process to direct RNAs to their final destination. In this review, we discuss recent findings from several different systems in an effort to clarify pathways and mechanisms that control the directed movement of RNA.

Indexed as

RNA TransportAnimalsBiological TransportCell PolarityDrosophilaDyneinsFemaleKinesinsMicrotubulesMolecular Motor ProteinsMyosinsOocytesRNARNA, MessengerRNA Processing, Post-TranscriptionalDyneinsKinesinsMolecular Motor ProteinsMyosinsRNARNA, Messenger

Identifiers

PMID21476929
PMCPMC3181154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.