Trial reportPsychopharmacology2011
Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia.
Trial report in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00136760 (Incentives Plus Bupropion for Smoking in Schizophrenics), which is not on this map. Cited by 40 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Incentives Plus Bupropion for Smoking in Schizophrenics
Who cites it
40 citing papers in PubMed, 9 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Korean Clinical Practice Guideline of Korean Society for Research on Nicotine and Tobacco (KSRNT) and National Evidence-based Healthcare Collaborating Agency (NECA) on Treatment of Tobacco Use 2024.Journal of Korean medical science · 2025Guideline
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020Pooled it
- Pooled it
- Incentives for smoking cessation.The Cochrane database of systematic reviews · 2019Pooled it
- Smoking cessation in severe mental ill health: what works? an updated systematic review and meta-analysis.BMC psychiatry · 2017Pooled it
- A review of the literature on contingency management in the treatment of substance use disorders, 2009-2014.Preventive medicine · 2016Pooled it
- Information and communication technology based prompting for treatment compliance for people with serious mental illness.The Cochrane database of systematic reviews · 2014Pooled it
- Interventions for smoking cessation and reduction in individuals with schizophrenia.The Cochrane database of systematic reviews · 2013Pooled it
- Systematic Review of Psychosocial Smoking Cessation Interventions for People with Serious Mental Illness.Journal of dual diagnosisPooled it
- Extending contingency management for smoking cessation to patients with or at risk for cardiovascular disease: A preliminary trial of a home-based intervention.Experimental and clinical psychopharmacology · 2024Trial
- Randomized clinical trial examining financial incentives for smoking cessation among mothers of young children and possible impacts on child secondhand smoke exposure.Preventive medicine · 2023Trial
- A preliminary investigation of schedule parameters on cocaine abstinence in contingency management.Journal of the experimental analysis of behavior · 2022Trial
- Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial.BMC medicine · 2019Trial
- Financial Incentives for Smoking Abstinence in Homeless Smokers: A Pilot Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018Trial
- Contingent vouchers and motivational interviewing for cigarette smokers in residential substance abuse treatment.Journal of substance abuse treatment · 2015Trial
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023Review
- Meta-Analysis on the Effect of Contingency Management for Patients with Both Psychotic Disorders and Substance Use Disorders.Journal of clinical medicine · 2021Review
- Treatment Outcomes of a Multi-Component Mobile Health Smoking Cessation Pilot Intervention for People with Schizophrenia.Journal of dual diagnosis · 2020Article
- Patient-Informed Treatment Development of Behavioral Smoking Cessation for People With Schizophrenia.Behavior therapy · 2019Article
- Contingency management and cognitive behavioral therapy for trauma-exposed smokers with and without posttraumatic stress disorder.Addictive behaviors · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
rationaleIndividuals with schizophrenia have high smoking-related morbidity and mortality rates and need powerful and innovative smoking cessation interventions.
objectivesThis proof-of-concept study investigated the feasibility and initial efficacy of combining a contingency management intervention with bupropion to reduce smoking in people with schizophrenia.
methodsUsing a double-blind, placebo-controlled, between-groups design, 57 non-treatment-seeking participants were randomized to receive 300 mg/day bupropion or placebo. One week later, participants were randomized to a contingency management (CM) intervention in which reductions in urinary cotinine levels were reinforced, or a non-contingent reinforcement (NR) condition in which session attendance was reinforced, regardless of cotinine level. Over the 22-day study period, participants visited the laboratory approximately three times per week to provide urine samples for analysis of cotinine levels, to give breath samples for analysis of carbon monoxide (CO) levels, and to report number of cigarettes smoked per day, nicotine withdrawal symptoms, cigarette craving, and psychiatric symptoms.
resultsCotinine and CO levels significantly decreased during the study period in participants randomized to the CM condition, but not the NR condition. Bupropion did not reduce cotinine levels or increase the efficacy of CM. Cigarette craving and psychiatric symptom levels significantly decreased during the study in all groups.
conclusionsThe results of this study indicate the efficacy and feasibility of this CM intervention for reducing smoking in individuals with schizophrenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.