ArticleChemical communications (Cambridge, England)2011
Which, if any, hydrates will crystallise? Predicting hydrate formation of two dihydroxybenzoic acids.
Article in Chemical communications (Cambridge, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- From polymorphs to cocrystals and salts: successfully predicting axitinib's challenging crystal forms.Chemical science · 2025Article
- 3D conformation and crystal interaction insights into drug development challenges for HCV drug analogues via molecular simulations.Communications chemistry · 2025Article
- Article
- Frontiers of molecular crystal structure prediction for pharmaceuticals and functional organic materials.Chemical science · 2023Review
- Metronidazole Cocrystal Polymorphs with Gallic and Gentisic Acid Accessed through Slurry, Atomization Techniques, and Thermal Methods.Crystal growth & design · 2023Article
- Co-Crystallization Approach to Enhance the Stability of Moisture-Sensitive Drugs.Pharmaceutics · 2023Review
- A data-driven and topological mapping approach for the a priori prediction of stable molecular crystalline hydrates.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- The Eight Hydrates of Strychnine Sulfate.Crystal growth & design · 2020Article
- Supramolecular Organization of Nonstoichiometric Drug Hydrates: Dapsone.Frontiers in chemistry · 2018Article
- Unraveling Complexity in the Solid Form Screening of a Pharmaceutical Salt: Why so Many Forms? Why so Few?Crystal growth & design · 2017Article
- Why do Hydrates (Solvates) Form in Small Neutral Organic Molecules? Exploring the Crystal Form Landscapes of the Alkaloids Brucine and Strychnine.Crystal growth & design · 2016Article
- Towards an understanding of the propensity for crystalline hydrate formation by molecular compounds.IUCrJ · 2016Article
- Can computed crystal energy landscapes help understand pharmaceutical solids?Chemical communications (Cambridge, England) · 2016Review
- Structural Properties, Order-Disorder Phenomena, and Phase Stability of Orotic Acid Crystal Forms.Molecular pharmaceutics · 2016Article
- Navigating the Waters of Unconventional Crystalline Hydrates.Molecular pharmaceutics · 2015Article
- Solid state forms of 4-aminoquinaldine - From void structures with and without solvent inclusion to close packing.CrystEngComm · 2015Article
- Insights into hydrate formation and stability of morphinanes from a combination of experimental and computational approaches.Molecular pharmaceutics · 2014Article
- Absorbing a Little Water: The Structural, Thermodynamic, and Kinetic Relationship between Pyrogallol and Its Tetarto-Hydrate.Crystal growth & design · 2013Article
- Complex Polymorphic System of Gallic Acid-Five Monohydrates, Three Anhydrates, and over 20 Solvates.Crystal growth & design · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A study of two dihydroxybenzoic acid isomers shows that computational methods can be used to predict hydrate formation, the compound:water ratio and hydrate crystal structures. The calculations also help identify a novel hydrate found in the solid form screening that validates this study.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.