ArticleInternational journal of general medicine2011
False positive seroreactivity to brucellosis in tuberculosis patients: a prevalence study.
Article in International journal of general medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The role of metagenomic next-generation sequencing in spinal infections: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Advancements and Applications of Lateral Flow Assays (LFAs): A Comprehensive Review.Sensors (Basel, Switzerland) · 2025Review
- Establishment of a 23S rRNA assay for Brucella and its application in evaluating bacterial growth status.Veterinary research communications · 2025Article
- Fulminant endogenous endophthalmitis caused byClinical case reports · 2023Article
- Brucellosis Masquerading as Disseminated Tuberculosis: A Clinical Case Report.The Permanente journal · 2023Article
- A Challenging Diagnosis of Febrile Pancytopenia in a Patient With a History of Autoimmune Disease.Cureus · 2023Article
- Is brucellosis a great mimic of tuberculosis? A case report.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Clinical Interpretation of Detection of IgM Anti-Polish journal of microbiology · 2019Article
- Seroprevalence and risk factors of brucellosis among slaughtered indigenous cattle, abattoir personnel and pregnant women in Ngaoundéré, Cameroon.BMC infectious diseases · 2018Article
- Seroprevalence and Associated Risk Factors of Brucellosis among Indigenous Cattle in the Adamawa and North Regions of Cameroon.Veterinary medicine international · 2018Article
- Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing.Journal of the Pediatric Infectious Diseases Society · 2017Article
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5 authors.
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Abstract
backgroundThe rising worldwide incidence of tuberculosis (TB) increases the demand for knowledge about its potential seroreactivity with other microbial agents. A few reports and the authors' experiences indicate that tuberculosis may result in a false-positive brucellosis serology. This may cause a diagnostic challenge because of the close clinical resemblance of these two infections.
objectiveThe aim of the present prevalence study was to elucidate brucellosis seroreactivity in patients with active TB.
methodsNinety-eight patients with newly diagnosed and active TB were studied using an enzyme-linked immunosorbent assay (ELISA) and Wright's and Coombs-Wright's tests. Seventy-five healthy individuals were used as controls. The patients showed signs of recovery after starting a standard anti-TB regimen and had no clinical evidence of brucellosis at a subsequent 6-month follow-up. The data were analyzed statistically by Fisher's exact test using SPSS 11.0.
resultsWe found that 9.2% of TB patients versus 1.3% of healthy controls had positive results on the anti-Brucella IgG ELISA (P = 0.04). Five TB patients were found to have agglutination on Wright's tests, while none of the controls showed agglutination.
conclusionActive TB patients may have some seroreactivity with Brucella antigens, and Brucella IgG ELISA may give a false positive in these patients. Clinicians should consider false positive brucellosis seroreactivity in patients with active TB.
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