Evidence map›Paper›PMID 21475185›Full record

ArticleNature2011

Cardiovascular disease: the diet-microbe morbid union.

Kimberly Rak, Daniel J Rader

Registry-linked trialAbstract readCommentNews
PubMed Publisher
In one paragraph

Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01817491 (Low Fat Vegan Diet or American Heart Association Diet, Impact on Biomarkers of Inflammation, Oxidative Stress and Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01817491 nacompletednot on this mapstarted 2013, after this paper: background citation

Low Fat Vegan Diet or American Heart Association Diet, Impact on Biomarkers of Inflammation, Oxidative Stress and Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol: A Four Week Randomized Trial

TypeinterventionalSponsorThe Cleveland ClinicRan2013 to 2014Enrolled60ConditionsCardiovascular Disease, Hypercholesterolemia, Obesity, Fatty LiverArmsAmerican Heart Association Diet, Reduced Fat Vegan Diet
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Probiotics: Potential Novel Therapeutics Against Fungal Infections.Frontiers in cellular and infection microbiology · 2021
    Review
  8. Review
  9. Article
  10. Plant-based diets and cardiovascular health.Trends in cardiovascular medicine · 2018
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Gut bacteria in health and disease.Gastroenterology & hepatology · 2013
    Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kimberly Rak
Daniel J Rader

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAtherosclerosisBetaineBiomarkersCardiovascular DiseasesCholineDietDietary FatsGastrointestinal TractHumansLiverMetabolomicsMethylaminesMiceOxygenasesPhosphatidylcholinesBetaineBiomarkersCholineDietary Fatsdimethylaniline monooxygenase (N-oxide forming)MethylaminesOxygenasesPhosphatidylcholinestrimethyloxamine

Identifiers

PMID21475185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.