Evidence map›Paper›PMID 21475079›Full record

Trial reportJournal of neurologic physical therapy : JNPT2011

Exercise and executive function in individuals with chronic stroke: a pilot study.

Patricia M Kluding, Benjamin Y Tseng, Sandra A Billinger

2 registry-linked trialsAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neurologic physical therapy : JNPT, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 44 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 6 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02956096 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Evaluation of Autonomic Modulation in the Hemiparetic Patients After Transcranial Direct Current Stimulation (tDCS) and Treadmill Training: Clinical Trial, Controlled, a Randomized, Double-blind

TypeinterventionalSponsorUniversity of Nove de JulhoRan2016 to 2017Enrolled30ConditionsStrokeArmsTranscranial direct current stimulation (tDCS), training on the running belt
NCT04154566 nacompletednot on this mapstarted 2019, after this paper: background citation

Influence of Aerobic Exercise on Inhibitory Control of Excutive Function in Spastic Hemiplegic Cerebral Palsy: A Randomized Controlled Trail

TypeinterventionalSponsorSouth Valley UniversityRan2019 to 2019Enrolled60ConditionsSpastic Hemiplegic Cerebral PalsyArmsAerobic Exercises
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  11. Exercise training and recreational activities to promote executive functions in chronic stroke: a proof-of-concept study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patricia M KludingDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, KS 66160, USA. pkluding@kumc.edu
Benjamin Y Tseng
Sandra A Billinger

Funding

WRITING AND WT LOSS MAINTENANCEM01RR023940 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI LEIDY, HEATHER J · 2007 to 2009
$6.6M
MOTION STUDY ANALYSIS WITH A SELSPOT II SYSTEMS10RR002394 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI PECKHAM, P. HUNTER · 1985 to 1985
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NCRR NIH HHS M01 RR 02394NCRR NIH HHS M01 RR023940
6 · The paper itself

Abstract

background and purposeEmerging evidence suggests that exercise may improve cognitive function in older adults. The purpose of this pilot study was to describe changes in measures of cognition and executive function in individuals with chronic stroke following participation in aerobic and strengthening exercise.

methodsA single-group, pretest-posttest design was used. Nine individuals with chronic stroke (mean age = 63.7 ± 9.1 years, mean time since stroke = 50.4 ± 37.9 months) completed a 12-week program of aerobic and strengthening exercise, 3 days per week. The primary outcome measures examined executive function (Digit Span Backwards and Flanker tests). Secondary measures examined various aspects of aerobic fitness (VO2peak and 6-minute walk distance) and function (Fugl-Meyer and 10-m walk speed).

resultsFollowing the intervention, significant improvements were found in the Digit Span Backwards test (mean change = 0.56 ± 0.9 digits; P = 0.05), Fugl-Meyer score (mean change = 3.6 ± 5.7; P = 0.05), and Stroke Impact Scale total score (mean change = 33.8 ± 38.5; P = 0.02). A significant correlation was found between improved aerobic capacity and improved performance on the Flanker test (r = 0.74; P = 0.02). DISCUSSION: The results of this study indicate that a 12-week aerobic and strengthening exercise program was associated with improvements in selected measures of executive function and functional capacity in people with stroke. Limitations of this study include the small sample size and lack of a comparison group.

conclusionsThis pilot study contributes to the emerging evidence that exercise improves cognition in people with stroke. These benefits indicate the need for future study with a larger group to have sufficient power to further explore these relationships.

Indexed as

CognitionExecutive FunctionStroke RehabilitationAgedChronic DiseaseExerciseExercise TherapyFemaleHumansMaleMiddle AgedNeuropsychological TestsPilot ProjectsTreatment Outcome

Identifiers

PMID21475079
PMCPMC3088429

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.