Evidence map›Paper›PMID 21474358›Full record

ReviewTransfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine2011

[Photochemical inactivation of pathogens in platelets and plasma: five years of clinical use in routine and hemovigilance. Towards a change of paradigm in transfusion safety].

J-P Cazenave

Abstract readEnglish AbstractReview
In one paragraph

Review in Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

J-P CazenaveÉtablissement français du sang Alsace, 10, rue Spielmann, BP 36, 67065 Strasbourg cedex, France. jeanpierre.cazenave@efs-alsace.fr

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transfusion of labile blood products is vital and essential for patients in absence of alternative treatment. Patients and doctors have always feared transfusion-transmitted infections by blood, blood components and blood-derived drugs. Photochemical inactivation of platelet concentrates and plasma, using a technique associating amotosalen and UVA, has been used for five years in a French region for the whole population and a large spectrum of patients, with efficacy and safety. It would seem wise to introduce labile blood products, submitted to pathogen inactivation by a technique already approved by a regulatory agency and not to wait for a perfect system including red blood cells concentrates. Universal implementation of pathogen inactivation in labile blood products is a major and key step to improve safety against infection in transfusion.

Indexed as

Blood PlateletsPlasmaUltraviolet RaysBlood BanksBlood-Borne PathogensBlood Component TransfusionBlood SafetyClinical Trials as TopicFranceFurocoumarinsHumansPhotochemistryPhotosensitizing AgentsPlatelet TransfusionSocieties, MedicalVirus InactivationamotosalenFurocoumarinsPhotosensitizing Agents

Identifiers

PMID21474358
PMCPMC7110539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.